The Segerfalk Symposium

Faculty of Medicine | Lund University



Neural reprogramming and disease modeling

Wednesday, May 8th, 2019




09.00 - 09.30


Registration (mandatory for all participants)

09.30 - 09.35


Welcome address
Henrik Ahlenius & Johan Jakobsson


Session chair: Daniella Ottosson

09.35 - 10.15


Jerome Mertens
Next-generation human neural reprogramming to study aging and sporadic Alzheimer’s Disease
University of Innsbruck, Austria and Staff Scientist at Salk Institute, San Diego, USA


10.15 - 10.35 


Short presentation # 1: Karolina Pircs
Modelling impaired autophagy in induced neurons derived from patients with HD
Molecular Neurogenetics lab, BMC A11


10.35 - 10.50


Coffee break


10.50 - 11.30


Moritz Mall
Ensuring neuronal identity during development and reprogramming
German Cancer Research Center and Hector Institute for Translational Brain Research, Heidelberg, Germany


11.30 - 11.50


Short presentation # 2: Janelle Drouin-Ouellet
Direct neural reprogramming of patient skin fibroblasts to study idiopathic Parkinson's disease
Montreal University, Faculty of Pharmacy


11.50 - 13.00


Lunch break (provided for registered participants)


Session chair: Karolina Pircs

13.00 - 13.40


Eva Hedlund
Unraveling fundamental aspects of motor neuron biology in health and ALS using Axon-seq and single cell RNA sequencing
Department of Neuroscience Karolinska Institute, Stockholm, Sweden


13.40 - 14.20


Short presentation # 3: Isaac Canals
Generation of human mature astrocytes to model neurological disorders
Stem Cells, Aging and Neurodegeneration Group, Lund Stem Cell Center

Short presentation # 4: Daniella Ottosson
Direct Reprogramming of glial cells into interneurons
Regenerative Neurophysiology, Lund Stem Cell Center


14.20 - 15.00 


Coffee break


Session chair: Isaac Canals


15.00 - 15.40


Volker Busskamp 
Engineering neuronal cell types from human stem cells
Center for Regenerative Therapies Technical University of Dresden, Germany

15.40 - 16.20


Silvia Cappello
Mechanisms regulating human neuronal migration
Max Planck Institute of Psychiatry, Munich, Germany


16.20 - 16.35 


Questions, discussion & concluding remarks

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