Molecular Neurogenetics

Faculty of Medicine | Lund University


Molecular Neurogenetics Jakobsson Lab


Illustration by: Bengt Mattsson

We are interested in how gene expression is regulated in the brain and how this process influence neurodegenerative diseases, psychiatric disorders and brain tumors. Our current focus is to study the role of epigenetic mechanisms and microRNAs. Our technical expertise include lentiviral vectors, transgenic mice and stem cells cultures.

Join us!

We are looking for one or more talented post-docs to join our team. Please contact Johan Jakobsson.


2019-01-24. Welcome to The Honorary Lecture in Genetics 2019 with Prof. Feng Zhang!

You are very welcome to join the upcoming honorary lecture with Prof. Feng Zhang sponsored by The Royal Physiographic and Mendelian Societies in Lund. For program - please open the attachment.
For registration (mandatory), please click here.

2019-01-23. Best Thesis Award 2017 goes to Rebecca Petri!
We're very happy to announce that our former PhD student Rebecca Petri has received the Best Thesis Award 2017 from the Neurobiology Section of Lund University. Well done, Rebecca!


2018-08-20. Nya rön om Huntingtons sjukdom publiceras

Läs här om vår senaste publikation som presenterar en direkt länk mellan Huntingtons sjukdom och en grundläggande process som kallas autofagi.

2018-03-02. Om att klippa och klistra i DNA / How to cut and paste in a gene sequence

På svenska: Är du nyfiken på hur vi arbetar med att klippa ut de dåliga generna och klistra in nya friska gener? Då kan den följande artikeln om ny genteknik och vår forskning vara mycket intressant!
In English: Are you interested in how we work with cutting out bad genes and pasting in new, healthy ones? In this case, you might find the below article on new gene techniques and our research very intersting!

2017-10-27. Congratulations Dr. Petri!

Congratulations to Rebecca Petri who defended her thesis "The Regulatory Role of microRNAs in the Mouse and Human Brain" today! We wish you all success in your future!

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rebecca petri

2017-06-26. New paper on large scale production of living brain cells

Are you interested in progress on large-scale production of living brain cells? You can find out more in our latest paper REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.

2017-10-09. Congratulations to Rebecca Petri!

Congratulations to Rebecca Petri who "nailed" her thesis today. We are very much looking forward to Rebecca's defence taking place on Oct 27th, 2017.

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rebecca cover

2017-03-17. UniStem Day 2017

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Today we took part UniStem Day 2017, together with dozens of other universities around Europe! UniStem is an annual event for the dissemination and outreach of stem cell science and research, conceived at the University of Milan. It is targeted to high school students and involves the collaboration of Universities as organising Entities. Fore more information about the event, please go to:

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2017-02-06. Viruses in the genome are important for our brain - new publication!

Please click here to read about our latest publication TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells.

Also, please click here to go to a short presentation of this research in Science:

På svenska: Ny publikation om virus som är viktiga för vår hjärna

2017-01-04. Vill du veta mer om så kallade retrovirus som under årmiljonernas gång kommit att infogas i människans DNA? Klicka här för Lunds Universitets pressmeddelande gällande vår nyaste publikation i Cell Reports TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells. 

Swedish Foundation for Strategic Research presents their film on Johan Jakobsson's research

2016-04-04. På svenska: Lunds Universitets pressmeddelande.

Swedish Foundation for Strategic Research

2016-02-03. In the spring of 2016 the Swedish Foundation for Strategic Research will present their Future Research Leaders in 17 new films, one researcher per week. Here you can see a taste of what's to come!

Welcome to "Genetic editing in regenerative medicine symposium"

2016-02-03. On May 11th, 2016, we will be welcoming a group of most excellent speakers who will present their finding during a whole-day seminar on Genetic editing in regenerative medicine. Participation is free of charge. The number of available spots is however limited - please register early to ensure your spot!

For more information please go the Segerfalk Symposium website here.

And she nailed it!

2015-10-01. Congratulations to Liana Fasching who "nailed" her thesis today! Liana's defense will take place on October 23rd, 2015, at 9.00 AM at the Segerfalk Lecture Hall, Sölvegatan 17 - everyone is welcome!

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Congratulations to the authors!

2015-09-29. Today we're celebrating our latest publication Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor by Marie E. Jönsson, Jenny Nelander Wahlestedt, Malin Åkerblom, Agnete Kirkeby, Josephine Malmevik, Per Ludvik Brattås, Johan Jakobsson and Malin Parmar. Congratulations to the authors, great job!

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Our research presented at Nordic Neuroscience

2015-06-15. Our colleagues Josephine Malmevik, Rebecca Petri and Per Ludvik Brattås have recently presented our work during the Nordic Neuroscience conference in Trondheim, Norway. Great work, great interaction, great conference!

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Congratulations Malin!

2015-04-09. Congratulations to Malin Åkerblom who has won the Crafoord award for the best 2014 PhD thesis of Lund University's Medical Faculty! Keep up the good work in the USA, Malin!

  • For more on the award please click here.

New Students

2015-02-03. Welcome to our two new students: Daniela Grassi & Sofia Madsen!

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New publication

2015-01-19. Stay updated with what's being written about our latest publication!

In English:

På svenska:

2014-12-29. Do you need a hint on Christmas reading? You might be interested in our new publication "TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells"!


Johan Jakobsson, PhD

Laboratory of Molecular Neurogenetics
Wallenberg Neuroscience Center
Lund Stem Cell Center
Lund University
221 84 Lund, Sweden
Phone: +46 46 222 42 25


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