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Bio-imaging

Our facilities provide the opportunity to study molecules, cells, organs and entire organisms.

Below you can see some examples of the bioimaging infrastructures available at Lund University.

Anterior chamber of the eye (ACE) platform

Direct visualization in a variety of tissues transplanted into the anterior chamber of the eye (ACE) provides a platform to screen drugs by performing long-term follow up and monitoring in target tissues. For access to competence and instruments please contact the ACE platform

ace

CLEM at IQ Biotechnology Platform

CLEM stands for Correlative Light and Electron Microscope (CLEM) that allows the simultaneous analysis of specimens by fluorescence and scanning electron microscopy. With this new technology, you can combine immunological and three-dimensional information within the same image. 

CLEM is the perfect tool to analyze unknown ultrastructures with a fast result, and to unravel complex relationships between structural and functional biological questions

We help you through the process, from preparation to analysis.

Read more: www.med.lu.se/clem

A scanning electron micrograph showing murine lung tissue.
A scanning electron micrograph showing murine lung tissue.

Image Core Facility at Immunology

The Section of Immunology provides users with advanced microscopes, image analysis software and technical support. The core facility is available for researchers at Lund University.

The facility includes:

  • Laser scanning confocal (LSM700)
  • Zeiss Axiovision
  • TIRF/ Spinning disc FLIM Inverted microscope (6 laser lines)

Contact: Lena_M.Svensson@med.lu.se

TIRF microscope

LBIC - Lund University Bioimaging Center

LBIC combines knowledge in the fields of medical physics, preclinical and clinical medicine, chemistry and technology in order to provide and develop imaging methods for the advanced study of morphology, cellular metabolism and physiological function in health and disease.

Modalities offered at LBIC:

  • MRI
  • PET/SPECT/CT
  • TEM/SEM electron microscopy/super-resolution light microscopy
  • National 7T facility for ultra high-field human MRI research

LBIC also offers training, support, workshops and seminars.

Read more: Lund University Bioimaging Center

Watch a video about LBIC

MAX IV

The MAX IV Laboratory serves 1000 users per year and deliver science in a broad range of fields including structure and dynamics of proteins in solution, protein crystallography and biomedical imaging.Since summer 2016 the new world leadning synchotron facility, MAX IV is up and running.

Read more: MAX IV

Image of MAX IV exterior

MedMAX a future part of the MAX IV Laboratory in Lund

MedMAX – a future beamline inside MAX IV, which will help us to study events and processes in tissues and materials using accelerators producing x-rays of very high intensity. MedMAX will be a super-eye capable of helping us understand biomedical problems. With its help, we can find new ways of discovering, diagnosing and treating diseases such as cancer, diabetes and osteoporosis.

Read more about the campaign: MedMAX

Read more about MedMAX

Watch a video about MedMAX

Microscopy Community at Lund University (MiCLU)

MiCLU is promoting imaging with a special focuson correlative 3D imaging with microscopy and microscopic analysisat Lund University. The main role of MiCLU is to provide planning for goodaccess at Lund University to advanced equipment and methods in microscopy andmicroscopic analysis. MiCLU works to promote co-ordination and synergismof existing infrastructure resources and planning and applications for newresources.

For more information visit MiCLU webpage

bacteria stor

Optical Projection Tomography - OPT

  • Do you want to create high-resolution 3D images of large specimen like mouse pancreas, liver, kidney, spinal cord or brain?
  • Do you want to aquire flourescent images and map the distribution of a flourescent protein/molecule of interest?

Then our expertise in OPT imaging could help you to answer your scientific question.

Read more: OPT imaging platform

opt animation 270

The Tissue Micro Array - TMA-center

The TMA-center offers high quality immunohistochemistry staining of tissue. Sample preparation and processing, embedding, sectioning, staining and scanning of the stained slides. We provides both single staining (one protein) and double staining (two proteins) performed with an Autostainer (Agilent/DAKO) automated system. The stained slides are scanned using an Aperio scanner.

The TMA-center also assembles TMA-blocks. A TMA block (Tissue Micro Array) is a block consisting of small cores from up to 96 different samples/cancers/tissues all organized in one block.

Contact: Kristina Ekström-Holka

kidney tissue
Kidney tissue stained with vimentin antibody.

Two-photon microscopy at BMC

This infrastructure allows imaging of tissues with very high temporal and spatial resolution. It consists of two microscopy stations: an ‘in vivo’ setup is used to image dynamic processes in the life mouse and an ‘ex vivo’ system designed to image thick live preparations, such as tissues that are not accessible to ‘in vivo’ microscopy. Both systems are available for LU and external users.

Read more: Two-photon-microscopy

2 photonmicroscope
Angela Cenci-Nilsson & Tim Fieblinger in the in vitro two-photon microscopy lab

Thanks to our world class research infrastructure, Lund University is well equipped to help lead the way towards future scientific breakthroughs. Your imagination is the only limit to what can be done.

Watch a video about our infrastructure

Watch a video about our infrastructure

Watch a video about our infrastructure

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