Tumor Microenvironment

Faculty of Medicine | Lund University


Selected publications

TEN SELECTED PUBLICATIONS, 2011- [Impact factor; No. of citations; Google Scholar, April 11, 2017].

1.          Christianson HC, Menard JA, Indira Chandran V, Bourseau-Guilmain E, Shevela D, Lidfeldt J, Månsson AS, Pastorekova S, Messinger J, BELTING M. Tumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity. Oncotarget (2017), Advanced Online Publication, April 07. [5.0; -]

2.          Hagman H, Bendahl PO, Melander O, Sundberg J, Johnsson A, BELTING, M. Vasoactive peptides associate with treatment outcome of bevacizumab-containing therapy in metastatic colorectal cancer. Acta Oncologica (2017) 17:1-8. [3.7; -]

3.          Bourseau-Guilmain E, Menard JA, Lindqvist E, Indira Chandran V, Christianson HC, Cerezo Magaña M, Lidfeldt J, Marko-Varga G, Welinder C, BELTING M. Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells. Nature Communications (2016) 20:11371-83. [11.5; 5]

4.          Menard JA, Christianson HC, Kucharzewska P, Bourseau-Guilmain E, Svensson KJ, Lindqvist E, Chandran VI, Kjellén L, Welinder C, Bengzon J, Johansson MC, BELTING M. Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan Dependent Endocytosis. Cancer Research (2016) 76:4828-4840. [8.6; 1]

5.          Melander O, Orho-Melander M, Manjer J, Svensson T, Almgren P, Nilsson PM, Engström G, Hedblad B, Borgquist S, Hartmann O, Struck J, Bergmann A, BELTING M.  Stable Peptide of the Endogenous Opioid Enkephalin Precursor and Breast Cancer Risk. Journal of Clinical Oncology (2015) 33:2632-8. [18.4; 4]

6.          Kucharzewska P, Christianson HC, BELTING M. Global profiling of metabolic adaptation to hypoxic stress in human glioblastoma cells. PLoS One (2015) 10:e0116740. [3.2; 22]

7.          Christianson HC, Svensson KJ, van Kuppevelt TH, Li JP, BELTING M. Cancer cell  exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity. Proceedings of the National Academy of Sciences USA (2013) 110:17380-5. Direct submission track. [9.7; 176]

8.          Svensson KJ, Christianson HC, Wittrup A, Bourseau-Guilmain E, Lindqvist E, Svensson LM, Mörgelin M, BELTING M. Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1. The Journal of Biological Chemistry (2013) 288:17713-24. [4.6; 145]

9.          Kucharzewska P, Christianson HC, Welch JE, Svensson KJ, Fredlund E, Ringnér M, Mörgelin M, Bourseau-Guilmain E, Bengzon J, BELTING M. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proceedings of the National Academy of Sciences USA (2013) 110:7312-7. Direct submission track. [9.7; 237]

10.         Svensson KJ, Kucharzewska P, Christianson HC, Sköld S, Löfstedt T, Johansson MC, Mörgelin M, Bengzon J, Ruf W, BELTING M. Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proceedings of the National Academy of Sciences USA (2011) 108:13147-52. Direct submission track. [9.7; 141] 

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