Oncology and Pathology

Faculty of Medicine | Lund University

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Theses

2017

  • Julien Menard Adaptive mechanisms in the hypoxic tumor microenvironment. Functional role of proteoglycans and identification of potential treatment targets
  • Martin Nilsson Treatment of BRCA1/2-associated breast cancer and identification of mutation carriers among breast cancer patients
  •  Richard Fristedt Prognostic role of the tumour microenvironment in esophago-gastric, pancreatic and periampullary adenocarcinoma: B cells and beyond
  • Philippe Wagner On the Epidemiology of Soft Tissue Sarcoma and Risk of Cancer following Knee prosthesis surgery. Important factors and methodological notes.
  • Björn Isfoss Histologic characterisation of stem cells in mammary epithelium and stroma
  • Helga Hagman A targeted approach to maintenance of tumour response. Clinical and translational studies in metastatic colorectal cancer.
  • Karolina Boman A valuable pair - candidate biomarkers RBM3 and PODXL in urothelial bladder cancer
  • Karin Elebro Androgen and Estrogen Receptors in Breast Cancer. Impact on Risk, Prognosis and Treatment Prediction.

2016

  • Helena Cirenajwis Molecular Subtypes of Melanoma. Biological and Clinical Significance.
  • Charlotta Hedner Prognostic biomarkers in upper gastrointestinal adenocarcinoma
  • Tove Wästerlid Burkitt lymphoma and diffuse large B-cell lymphoma – therapeutic strategies and pathogenetic mechanisms.
  • Carina Forsare Prognostic factors in breast cancer with focus on proliferation and non-linear effects
  • Maria Simonsson Integration of Tumor and Host Factors – Implications for Breast Cancer Prognosis
  • Jacob Elebro Prognostic factors in periampullary adenocarcinoma. A retrospective study over an 11 year period.
  • Fredrik Ellin Clinical factors and outcome in T-cell lymphoma: a population-based perspective
  • Jenny-Maria Jönsson Intrinsic subtypes and prognostic implications in epithelial ovarian cancer
  • Patrick Joost Mismatch Repair Deficient Cancer Diagnostic Aspects in Colorectal Cancer and the Role of Urological Cancer in Lynch Syndrome

2015

  • Mattias Aine Epigenetic and Phenotypic Profiling of Urothelial Carcinoma
  • Andrea Markkula Genetic factors, body constitution, and tumor characteristics in relation to breast cancer prognosis
  • Sven-Erik Olofsson Testicular cancer – response adapted treatment, prognostic markers and survivorship issues
  • Anna Larsson Discovery and validation of podocalyxin-like protein as a prognostic biomarker in colorectal cancer
  • Erika Elgström Radioimmunotherapy in an Immunocompetent Tumor Model utilizing a 177Lu-mAb
  • Johanna Sjövall PET in the evaluation of head and neck cancer treatment - management of the neck
  • Inga Newie MicroRNAs in HER2-Amplified Breast Cancer
  • Eleonor Olsson Molecular Analysis of Breast Cancer Transcriptomes, Genomes, and Circulating Tumor DNA
  • Karin Fjordén Prognostic Markers and Mechanisms of Chemotherapy Resistance in Diffuse Large B-cell Lymphoma

2014

  • Helena Christiansson Mechanistic studies on the role of extracellular vesicles in the tumor microenvironment
  • Liv Ben Dror A high-throughput pathology approach for further insight into the role of RBM3 as a biomarker of prognosis and chemotherapy response in human cancer
  • Siker Kimbung Metastatic Breast Cancer: Biomolecular Characterization and Targeted Therapy
  • Carolina Ellberg Insights into breast cancer: New familial patterns and identification of a potential predictive marker
  • Jenny Brändstedt Associations of sex, anthropometric and reproductive factors with clinicopathological and molecular characteristics of colorectal cancer

2013

  • Sophie Eriksson Radioimmunotherapy of Metastatic Disease - Studies of Alpha- and Beta-particle-Emitting Radionuclides in a Preclinical Model
  • Marie Klintman The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer
  • Ida Johansson Molecular Characterization of Male Breast Cancer
  • Gottfrid Sjödahl Molecular Classification of Bladder Cancer

2012

  • Katrin Svensson Mechanistic Studies On the Role of Polyamines and Microvesicles in Tumor Growth and Hypoxia-mediated Angiogenesis
  • Susanne Magnusson Genetic factors in childhood cancer. Associations between tumors in childhood and adulthood, and prevalence of germline TP53 mutations
  • Bo Attner Register studies of cancer in the Southern Health Care Region in Sweden
  • Sara Alkner Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer.
  • Helle Vendel Petersen Mutation Carriers' Perspectives on Lynch Syndrome; self-concept and lived experiences.
  • Katja Harbst Genomic analysis of primary and metastatic malignant melanoma

2011

  • Katarina Sjövall Living with cancer - Impact on cancer patient and partner
  • Katarina BartumaTowards Improved Management of Lynch Syndrom; Ovarian cancer profiles, risk perception, knowledge and family perspectives
  • Karolina Holm Genetic and epigenetic characterisaton of breast tumours
  • Ana Carneiro Refined diagnosis and prognosis in soft tissue sarcoma - genetic profiles, biomarkers and prognostic models

2010

  • Adalsteinn Gunnlaugsson  Chemoradiation in Gastrointestinal Cancer
  • Maria Hietala  Impact of Lifestyle, Hormones, and Genes on Breast Cancer
  • Johan Staaf  Genomic profiling of breast cancer by microarray-based technology and bioinformatics
  • Anna Isinger Ekstrand Genomic Profiling, Mutations and Deranged Signaling in Esophageal Cancer and Hereditary Colorectal Cancer
  • Maria Bjurberg FDG-PET in Cervical Cancer - Translational Studies
  • Johanna Welch  On the Role of Polyamines and Microvesicles in Tumour Development. Regulation by Hypoxia and Implications for Therapeutic Intervention of Cancer.
  • Maria Henningson Genetic polymorphisms, IGF-1, and oral contraceptive use in women from high-risk breast cancer families 
  • Fredrika Killander Radiotherapy in Early Breast Cancer

2009

  • Emma Niméus  Prognostic and treatment predictive factors for radio- and chemotherapy resistance in breast cancer patients- a step towards personlized medicine
  • Anders Wittrup  Endocytosis of therapeutic macromolecules in tumor cells - Mechanistic aspects of the proteoglycan receptor function
  • Helena Persson  Small non-coding RNAs in cancer

2008

  • Erika Bågeman Genetic polymorphisms in breast cancer in relation to risk and prognosis
  • Gabriella Honeth Stem and progenitor cells in brain ad breast malignancies
  • Linda Mårtensson High-Dose Radioimmunotherapy and Extracorporeal Depletion in A Syngeneic Rat Tumor Model

2007

  • Josefin Fernebro Soft Tissue Sarcoma Patterns multiplicity, heterogeneity and growth characteristics
  • Princy Francis Genetic Profiling in Soft Tissue Sarcoma
  • Britta Halvarson Morphological Features and Mismatch Repair in Colorectal Tumors. Dept of Pathology and Oncology
  • Susanne Malander Hereditary Ovarian Cancer, mutation frequencies and genetic profiles
  • Ann Rosendahl Insulin-like Growth Factor System functional role and regulation in carcinomas 
  • Johan Linderoth Diffuse large B-cell lymphoma - tumour characteristics on RNA and protein level associated with prognosis

2005

  • Göran Jönsson Genetic characterization of malignant melanoma and breast cancer
  • Sofia Gruvberger Saal Estrogen receptor alpha and beta in breast cancer - gene expression profiles and clinical implications
  • Christina Carlsson Advocates and Voices. Swedish patient associations, their importance to individuals with cancer and collaboration with health care.
  • Zhongmin Wang RADIOIMMUNOTHERAPY & EXTRACORPOREAL ADSORPTION Preclinical Studies of the Pharmacokinetics & Biotinylation of Radioimmunoconjugates in Immunocompetent Rats
  • Johan Vallon-Christersson Functional and Molecular Characterization of BRCA1 and BRCA2 Associated Breast Cancer
  • Kajsa Ericson Tumors associated with HNPCC: Defective Mismatch Repair and Familial Risk of Cancer

2004

  • Jacob Engellau Prognostic factors in soft tissue sarcoma Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence
  • Karin Rennstam Molecular cytogenetics in sporadic breastcancer
  • Ingrid Idvall Ductal carcinoma in situ of the breast. Histopathological and cell biological factors: their relationship To mode of detection and to subsequent ipsilateral and contralateral tumours.

2003

  • Niklas Loman Clinical aspects of hereditary breast cancer
  • Eva Fernebro Rectal cancer: tumor biology and prognostic markers
  • Sara Kinhult Endothelial and cardiac effects of 5-fluorouracil
  • Thomas Relander Retroviral gene transfer to repopulating hematopoietic cells

2002

  • Ola Linden Radioimmunotherapy of B-cells lymphoma. Clinical studies with anti CD-22 antibodies.
  • Maria Planck Hereditary nonpolyposis colorectal cancer. Molecular genetics and biology of associated tumours.
  • Ingrid Hedenfalk Gene expression profiling of hereditary breast cancer.

2001

  • Anjila Koul Molecular genetic alterations in endometrial and ovarian cancers.

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