The Division of Molecular Medicine and Gene Therapy is located at the Biomedical Center (BMC), Lund University, Sweden. Established as a joint venture between the Medical Faculty at Lund University and the Hematology Clinic at Lund University Hospital, our mission is to translate basic science to clinical applications.
Our research focuses on hematopoiesis, the continuous and dynamic process of blood cell formation. The laboratory consists of eight closely collaborating research groups that all share a common interest in investigating the properties of blood stem cells to eventually understand and treat hematological disorders.
Five of our researchers belong to the Hemato-Linné Excellence Linnaeus Research Environment funded by The Swedish Research Council and Lund University. Several of the groups are engaged in StemTherapy, a Strategic Research Area for Stem Cells and Regenerative Medicine that is also supported by The Swedish Research Council.
Professor Timothy M Cox from the Department of Medicine, University of Cambridge, United Kingdom will be visiting Lund on September 9 - 12, 2015.
He will give a lecture entitled "Innovative therapies for Gaucher disease" on Thursday September 10 at 16:00 in Segerfalk lecture hall, BMC A10.
Please welcome Jun Chen, who joined the Flygare group from Jichi University, Japan.
"My PhD research in Tetsuro Yamamoto’s group at Kumamoto University of Japan focused on ribosomal protein S19 (RP S19). RP S19 is a component of the small subunit and essential for ribosome biogenesis. Cellular RP S19 is inter-molecularly cross-linked by an intracellular transglutaminase during apoptosis, and plasma RP S19 is similarly cross-linked by activated coagulation factor XIII during blood coagulation, forming an isopeptide bond between Lys122 and Gln137. We have previously demonstrated that the cross-linked RP S19 oligomers gain a ligand capacity to the C5a receptor (C5aR) and express various kinds of extra-ribosomal functions. Furthermore, my research supports an interesting hypothesis that cross-linked oligomers of RP S19 play an essential role in definitive erythropoiesis as a ligand of the C5aR of erythroblasts and macrophages."
The application period for the Preparatory Program in Stem Cell Biology 2016 is now open. The application deadlines for round 1 and round 2 are August 17th, 2015 and October 15th, 2015, respectively.
Blood transfusions are vital, but demand for blood far exceeds supply all over the world. In India and China, for example, relatives are usually called upon to give blood in the case of an accident or an operation. An international conference in Lund, Sweden, the first of its kind, will now discuss various possible alternative treatment methods with the potential to complement or even replace blood transfusion. These alternatives include re-programmed skin cells and haemoglobin from sugarbeet.