The Division of Molecular Medicine and Gene Therapy is located at the Biomedical Center (BMC), Lund University, Sweden. Established as a joint venture between the Medical Faculty at Lund University and the Hematology Clinic at Lund University Hospital, our mission is to translate basic science to clinical applications.
Our research focuses on hematopoiesis, the continuous and dynamic process of blood cell formation. The laboratory consists of eleven closely collaborating research groups that all share a common interest in investigating the properties of blood stem cells to eventually understand and treat hematological disorders.
Six of our researchers belong to the Hemato-Linné Excellence Linnaeus Research Environment funded by The Swedish Research Council and Lund University. Several of the groups are engaged in STEMTHERAPY, a Strategic Research Area for Stem Cells and Regenerative Medicine that is also supported by The Swedish Research Council.
Miharada et al. could report the identification of a novel regulator of hematopoietic stem cell function, developmental pluripotency-associated 5 (Dppa5), in the latest volume of Cell Reports. Miharada and colleagues discovered a novel connection between endoplasmic reticulum stress and hematopoietic stem cell properties, implicating that protein quality control is critical for hematopoietic stem cell function in vivo and in vitro.
Göran Karlsson has been awarded The Swedish Cancer Society's Young Investigator Award 2014. The prestigious Young Investigator Award provides a 6-year funding to promising young researchers who are in the process to establish their independent research group.
The Swedish Society for Medical Research (SSMF) has awarded Göran Karlsson with their big grant for young researchers. The purpose is to allow young promising scientists to start up and establish their own independent research group. The aim with Görans research is to identify key factors to distinguish blood stem cells from leukemic stem cells.