MoReLife

Faculty of Medicine | Lund University

MoReLife

About the MoReLife Research Initiative

Our scientific challenge for the future is to provide complete descriptions of cell signaling pathways that pinpoint targets for intervention. To reach this goal, we take a holistic approach to integrate the molecular and systems levels to encompass a hierarchy of complexity from molecules to intact tissue. The initial focus is on host-pathogen interactions, immune regulation and tissue remodeling, which are areas of wide relevance for healt h and disease. In addition, we define four technology areas that are essential for solving the medical research problems:

maxlab lu
  •  Systems biology & "omics"
  •  Protein structure & recognition
  •  Molecular probes & drug design
  •  Bioimaging & in vivo models

Our aim is to establish a Resource Center to contribute expertise and technology to the research programs and other users. The Resource Center will be open to industry on a commercial basis, providing access to facilities that are unattainable for small/medium sized companies. We are enthusiastically supported by the public health and biotech-pharma business sectors, making us confident that this strategy will generate a new research arena for the benefit of Swedish industry.

LP3: A Protein-Production Platform at Lund University

New network of Swedish protein production facilities

LP3 is taking part in the formation of a new network of Swedish protein production facilities together with the Protein Science Facility at Karolinska Institutet/SciLifeLab, Mammalian Protein Expression at Göteborg University, Protein Expertise Platform at Umeå University and the Drug Discovery and Development platform at SciLifeLab. The network will coordinate optimized use of resources and facilitate increased knowledge transfer.

LP3 is in operation from February 2012

LP3 is a new Lund University trans-faculty facility for protein expression, production and isolation. The platform is integrated with research training and development of skills in production, purification and experimental analysis of proteins. Establishment of the facility was initiated by the MoReLife network. The facility is in operation from February 2012 with financial support from the Vice Chancellor of Lund University, MoReLife (in turn financed by the Medical faculty), LUDC/EXODIAB, CMPS and the Department of Biology.

LP3 provides protein overexpression and purification services to life scientists in the region. This will enable more scientists to bring their research to the molecular/structural regime, thus making the coming MAX IV and ESS developments more accessible to our researchers in the medical/biochemical/biological sphere.

The facility will utilize and add to the outstanding competence and infrastructure available at Lund University, in its Faculties of Medicine, Science, and Engineering together with MAX-lab.

MoReLife hosted a number of open networking symposia during 2010, during which we discussed the need for and requirements on a protein factory. We have conducted a broad survey on future protein needs (below), and a retreat.

The Protein-Production Facility was Awarded 3.4 Million SEK

Out of the 10 MSEK made available by Lund University for research infrastructure, MoReLife was granted 3.4 MSEK for the establishment of a protein-production platform at LU. The decision was made by the vice chancellor on June 16 2011, following the recommendation of the Council for Infrastructure (Infrastrukturrådet). Together with prior investments this enables us to initiate the implementation process of the facility, and recruitment of platform personnel will commence after the summer break.

Survey on Protein-Production Needs

During Dec 2010-Jan 2011, we conducted a survey of the protein needs in the region, encompassing 250 research group leaders. We targeted life scientists who work with proteins, or who might come to work with proteins in the future. The response was overwhelming: over 80 research leaders responded, specifying hundreds of proteins of scientific interest.

Events

2014-05-20

MicroMAX and MedMAX - an introduction to opportunities for biomedical science at MAX IV

hosted by MoReLife and the MAX IV Laboratory

Tuesday 20th of May

Venue: Lundmarksalen, Astronomihuset, Sölvegatan 27, Lund

Please register no later than the 12th of May by sending an email to

Kajsa M Paulsson

kajsa_m.paulsson@med.lu.se

2014-03-01

New network of Swedish protein production facilities

LP3 is taking part in the formation of a new network of Swedish protein production facilities together with the Protein Science Facility at Karolinska Institutet/SciLifeLab, Mammalian Protein Expression at Göteborg University, Protein Expertise Platform at Umeå University and the Drug Discovery and Development platform at SciLifeLab. The network will coordinate optimized use of resources and facilitate increased knowledge transfer.

2013-09-30

New possibilities at LP3! 

Lund Protein Production Platform (LP3, www.lu.se/lp3) has new staff and opens a call for nomination of new protein production pilot projects

Make sure to indicate your interest before the 17th October by sending an e-mail to wolfgang.knecht@biol.lu.se 

2013-03-27 

Meeting 

'Neutrons and Life Sciences' 2013 May 29-31 

Are you curious about what neutrons and ESS can contribute to the life sciences? Now is your chance to learn more, offer your input and meet with people using neutrons in life science today – here in Lund! This ESS Science Symposium

 will bring together current and potential users of neutron techniques in the biomedical sciences to discuss common challenges and future opportunities at ESS.

When? 2013-05-29 - 2013-05-31

Where? Lund

Welcome!

Hosted by ESS, University of Copenhagen and the MoreLife Network at Lund University

Contact: Jens Lagerstedt

jens.lagerstedt@med.lu.se

2013-01-22

Meeting

'Planning the Lund University Microscopy Platform'

2012-11-15  

Seminar

"Finding needles from haystack: Identification of disease-related variations" 

Professor Mauno Vihinen, Experimental Medical Sciences, Lund University

When? 2012-11-15 at 15.15

Where? Main lecture hall, Biology building/"Biologihuset" A, Sölvegatan 35, Lund

Welcome!

 Hosted by Molecular cell biology seminar series and 

Molecular Recognition in Life (MoReLife) 

Contact: Claes von Wachenfeldt

claes.von_wachenfedlt@biol.lu.se

2012-10-15

Microscopy Needs Survey 

Dead line: 2012-10-25 

Link: Survey Microscopy Needs

Organiser: LBIC/MoReLife

Contact: Kajsa Paulsson, 

Kajsa_M.Paulsson@med.lu.se

2012-08-15

SciLifeLab-Stockholm information meeting 

Time: 2012-10-25 Kl 10.00-12.00

Place: Segerfalksalen, BMC, Sölvegatan 19, Lund 

Organiser: MoReLife

Contact: Kajsa Paulsson, 

Kajsa_M.Paulsson@med.lu.se

“SciLifeLab Stockholm”

Welcome to SciLifeLab Stockholm information meeting in Lund!

During the spring 2012 MoReLife arranged a successful meeting in Lund with SciLifeLab Uppsala Program MoReLife 120424 (pdf 57,4 kB). Now, following an invitation from the MoReLife network, members of SciLifeLabs in Stockholm will be visiting Lund on October 25. The SciLifeLab-information meeting aims to inform life science researchers and other interested parties in Lund/Malmö about the technology platforms and services at SciLifeLab that are available to all researchers in Sweden. Learn more at www.scilifelab.se.

For full program

2012-04-02

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