The Division of Molecular Medicine and Gene Therapy is located at the Biomedical Center (BMC), Lund University, Sweden. Established as a joint venture between the Medical Faculty at Lund University and the Hematology Clinic at Lund University Hospital, our mission is to translate basic science to clinical applications.
Our research focuses on hematopoiesis, the continuous and dynamic process of blood cell formation. The laboratory consists of ten closely collaborating research groups that all share a common interest in investigating the properties of blood stem cells to eventually understand and treat hematological disorders.
Six of our researchers belong to the Hemato-Linné Excellence Linnaeus Research Environment funded by The Swedish Research Council and Lund University. Several of the groups are engaged in StemTherapy, a Strategic Research Area for Stem Cells and Regenerative Medicine that is also supported by The Swedish Research Council.
Each year UniStem organizes a big outreach event on stem cells dedicated to high school students. In 2014 the event was organized simultaneously by 47 universities across Italy, Spain, Ireland, Sweden and UK and the plan is to get even more universities across Europe involved for 2015. This year Lund Stem Cell Center, via the Research School, will organize UniStem Day in Lund! The event will take place on Friday March 13th.
Please welcome Xiaojie Xian! Xiaojie joined the vector unit headed by Niels-Bjarne Woods as a senior researcher and will also work part-time for the department as a lab manager.
"I was working extensively with in vivo mouse system to explore the mechanism of tumour metastasis and pancreas development for my PhD study. During my post-doc time at Copenhagen University, my projects involved in studying the signaling of integrin and/or syndecans in various cellular systems. My research project at Stefan Jovinge’s group, Stem Cell Center was aiming at directed differentiation of human ES/iPS cells into cardiomyocytes and identifying the surface markers for different population of cardiomyocytes." Xiaojie Xian
Johan Flygare and Kenichi Miharada together with Leif Bülow from the Division of Pure and Applied Biochemistry are organising a cross-disciplinary conference on transfusion medicine in June 2015 in Lund. This conference will bring together world-leading scientists in an effort to discuss the latest research highlights from different research areas in the field of transfusion medicine.
Please welcome Linda Geironson Ulfsson to the Stem Cells and Leukemia group. Linda joined us from the Antigen Presentation group headed by Kajsa Paulsson at Lund University.
"The main purpose of my PhD project was to elucidate how the HLA class I dedicated chaperone, tapasin, mediates the quality control of HLA class I maturation in order to clarify which peptides are selected for presentation at the cell surface. A recombinant part of tapasin was shown to facilitate folding of different HLA class I allomorphs in a peptide- and allomorph-dependent manner. The aim of the project I will work on at the Molecular Medicine and Gene Therapy department is to identify and target leukemic stem cells in chronic myeloid leukaemia." Linda Geironson Ulfsson
The Swedish Society for Medical Research (SSMF) has awarded Sofie Singbrant Söderberg with their big grant for young researchers. The purpose is to allow young promising scientists to start up and establish their own independent research group. The aim of Sofie’s research is to discover novel strategies to increase red blood cell production to treat refractory anemia.