The Division of Molecular Medicine and Gene Therapy is located at the Biomedical Center (BMC), Lund University, Sweden. Established as a joint venture between the Medical Faculty at Lund University and the Hematology Clinic at Lund University Hospital, our mission is to translate basic science to clinical applications.
Our research focuses on hematopoiesis, the continuous and dynamic process of blood cell formation. The laboratory consists of eight closely collaborating research groups that all share a common interest in investigating the properties of blood stem cells to eventually understand and treat hematological disorders.
Five of our researchers belong to the Hemato-Linné Excellence Linnaeus Research Environment funded by The Swedish Research Council and Lund University. Several of the groups are engaged in StemTherapy, a Strategic Research Area for Stem Cells and Regenerative Medicine that is also supported by The Swedish Research Council.
Blood transfusions are vital, but demand for blood far exceeds supply all over the world. In India and China, for example, relatives are usually called upon to give blood in the case of an accident or an operation. An international conference in Lund, Sweden, the first of its kind, will now discuss various possible alternative treatment methods with the potential to complement or even replace blood transfusion. These alternatives include re-programmed skin cells and haemoglobin from sugarbeet.
In October 2014, the two Hemato-Linné researchers Mikael Sigvardsson and Stefan Karlsson were awarded a prestigious Knut and Alice Wallenberg grant each for research projects with high scientific potential. In an interview series, the Knut and Alice Wallenberg Foundation now reports about the aims, challenges, and future implications of the respective projects.
Please welcome Hooi Min Tan Grahn! Hooi Min joined the Karlsson group from the Joslin Diabetes Center, affiliated Harvard Medical School, Boston, and will be embedded in the Wallenberg project. The aim of the project is to understand the rules for how the stem cell compartment is organized to sustain regeneration throughout life.
Congratulations to Mattias Magnusson, Kenichi Miharada, and Sofie Singbrant Söderberg, who altogether were awarded grants worth 4.2 million SEK.
Kenichi Miharada and Mattias Magnusson received 2 million SEK each from the Kamprad Family Foundation for their work on cancer-related anemia and individualised cancer treatment, respectively. Sofie Singbrant Söderberg was awarded 200.000 SEK project support from the Clas Groschinsky Foundation for identifying novel mechanisms to treat MDS-related refractory anemia.