Molecular Medicine and Gene Therapy

Faculty of Medicine | Lund University


Molecular Medicine and Gene Therapy

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The Division of Molecular Medicine and Gene Therapy is located at the Biomedical Center (BMC), Lund University, Sweden. Established as a joint venture between the Medical Faculty at Lund University and the Hematology Clinic at Lund University Hospital, our mission is to translate basic science to clinical applications.

Our research focuses on hematopoiesis, the continuous and dynamic process of blood cell formation. The laboratory consists of eight closely collaborating research groups that all share a common interest in investigating the properties of blood stem cells to eventually understand and treat hematological disorders.

Five of our researchers belong to the Hemato-Linné Excellence Linnaeus Research Environment funded by The Swedish Research Council and Lund University. Several of the groups are engaged in StemTherapy, a Strategic Research Area for Stem Cells and Regenerative Medicine that is also supported by The Swedish Research Council.


gerald de haan

Professor Gerald de Haan from the University Medical Center Groningen, The Netherlands, will be visiting Lund on June 3 in connection with Matilda Billing's thesis defence.

He will give a lecture entitled "Aging of hematopoietic stem cells" on Friday June 3 at 11 am in the Segerfalk Lecture Hall, BMC A10.

Host: Stefan Karlsson


Matilda Nifelt Hägerström

Matilda Billing will defend her thesis entitled "Pathways that govern hematopoietic stem cell fate" on June 3 at 13:30 in the Belfrage Lecture Hall, BMC D15. 

Faculty opponent: Professor Gerald de Haan, Department of Stem Cell Biology, University Medical Center Groningen, The Netherlands

Main supervisor: Professor Stefan Karlsson

Chair: Professor Urban Gullberg


julia petersson

Please welcome Julia Petersson to the Karlsson group. Julia will be working on a summer project about calcium signalling and its role in hematopoietic stem cell maintenance under the supervision of Hooi Min Tan Grahn, postdoctoral fellow in Stefan Karlsson's group. 

Welcome to our division Julia!

graphical abstract camp saxena
Graphical abstract. Stem Cell Reports DOI:10.1016/j.stemcr.2016.03.006

Congratulations to Shobhit Saxena and colleagues, whose paper "Cyclic AMP Signaling through Epac Axis Modulates Human Hemogenic Endothelium and Enhances Hematopoietic Cell Generation" has been published in Stem Cell Reports. In this study, Shobhit Saxena, a former postdoc in the Woods group, could demonstrate a previously unrecognised role of cyclic AMP signaling in regulating human hematopoietic development.

- These findings advance the mechanistic understanding of hematopoietic development toward the development of transplantable human hematopoietic cells for therapeutic needs, says Niels-Bjarne Woods, last author of the study.

Congratulations to all authors!

Ulrika Blank Savukinas' artistic interpretation of Valgarður Sigurðsson et al's work made the cover of the latest issue of Cell Stem Cell. Congratulations!

- This is a great honor for us. Nowadays there are so many publications; ending up on the journal cover captures the reader’s interest for our work, says Kenichi Miharada, last author of the study.

  • Read the original article here.
cover cell stem cell

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