Faculty of Medicine | Lund University


Neurobiology: Björklund Group


anders bjo rklund

Anders Björklund, Professor, Head of the Neurobiology Unit

Development of restorative and neuroprotective treatment strategies for Parkinson´s disease

Our research aims at developing new restorative and neuroprotective treatments for neurodegenerative diseases using cell transplantation and direct in vivo gene delivery.

The Neurobiology Unit seeks to develop techniques for isolation and identification of neural progenitor cells with the capacity to generate fully functional dopamine neurons after transplantation to the Parkinsonian brain. We use cell sorting and cell engineering techniques to generate dopamine neuron precursor cells specifically for transplantation purposes, and explore techniques for insertion of genes into stem cells to direct the development of stem cells into transplantable midbrain dopamine neurons.

In a second line of research we explore rodent models of Parkinson´s disease to study the mechanisms underlying development of L-DOPA-induced dyskinesias, and use recombinant viral vectors as tools to model Parkinson-like neurodegeneration in rodents, and for delivery of putative therapeutic factors, GDNF and Nurr 1 in particular, to the brain.


2016-05-12. New publication available
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.

2015-06-03.  On new therapeutic principle for Parkinsonian dyskinesia.
To learn more about the results of a new treatment study which Anders Björklund's lab participated in, please see the following Lund University Neuroscience Newsletter, 1/2015:

2015-02-11. På svenska: Ny publikation
Här kan du läsa om en ny behandlingsprincip mot ofrivilliga rörelser vid Parkinsons och vår senaste publikation "Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study".

2014-05-27. Talk by Anders Björklund
Are you interested in Nurr1 and Parkinson's Disease? Below please find a talk on this topic by the 2013 ECNP Neuropsychopharmacology Award winner Anders Björklund.

2012-11-27. På svenska: Transplantation av hjärnceller i början på 2013.
Inom ramen för europastudien TRANSEURO kommer fem Parkinsonsjuka patienter att genomgå transplantationer av hjärnceller i Lund i början på 2013.
Läs mer därom här, i "Vetenskap & hälsa" här eller i Sydsvenskan här.
Se SVTs inslag här.

2012-10-17. På svenska: Med siktet på nya behandlingar av Parkinsons sjukdom.
Vetenskap & Hälsa om Anders Björklunds forskning på Parkinsons sjukdom.

2012-03-30. Interview with Anders Björklund
When PARKINSON’S MOVEMENT went to Sweden in October 2011, they also did some filming where PM’s Jon Stamford interviewed the researchers of Bagadilico and MultiPark at Lund University. Here is the first of the interview films where Jon interviews Anders Björklund.

2011-09-12. Brain cell transplants win Fernström Prize
This year's Fernström Foundation Nordic Prize goes to Professor Anders Björklund.

2011-05-10. Anders Björklund joins the National Academy of Sciences.

Site overview