TRAINS is a joint platform for the members in the two research groups TNU and BRAINS. It aims to provide continuous scientific training for the research students and postdoctoral fellows as well as a general meeting point with technical and administrative staff. In these regular meetings, joint research activities are discussed and members of the research groups give talks on ongoing or completed research projects.Invited speakers from outside the groups give talks in the area of neurodegeneration and psychiatric illness.
Here is the schedule for the TRAINS talks and meetings during spring 2012:
| February 14 | Sofia Hult: The role of mutant huntingtin in leptin receptor-expressing neurons for psychiatric-like features and the metabolic phenotype in Huntington’s disease |
| February 21 | Gürdal Sahin: L-DOPA derived dopamine in the Parkinsonian state: Where is the origin and what are the targets? |
| March 6 | Seminar with Dr Doris Doudet, University of British Columbia, Vancouver, Canada |
| March 20 | Sanaz Gabery: Investigations of hypothalamic changes in the Image-HD study |
| April 3 | Lauren Broom: Methods for determining tyrosine hydroxylase (TH) enzyme function in vitro |
| April 19 | Lab discussions |
| May 21 | Lab discussions |
| May 29 | Lab discussions |
| June 5 | TRAINS Retreat at Häckeberga slott |
| June 26 | Merve Özgür: DA dysregulation in Huntington's Disease |
The following talks have taken place at TRAINS meetings:
Fall 2011
Merve Özgür, BRAINS: Exploration of dopamine release and reuptake mechanisms in the Parkinsonian rats transplanted with serotonin and dopamine neurons.
Sanaz Gabery, Sofia Hult and Rana Soylu, TNU: Report from the World Congress of HD in Melbourne, Australia
Elisabeth Nikitidou, BRAINS: Post-fixation time – An important factor for immunohistochemical stainings?
Dr. Joe Flores, BRAINS: Human Retinal Pigment Epithelial Cell Transplantation for the treatment of Parkinson's Disease.
Dr. Kerstin Buck, BRAINS: Development of highly specific and sensitive methods for the measurement of oxidative stress markers in Parkinson's disease.
Spring 2011
Dr. Gabrielle Callander, BRAINS: Viral Vector and Gene Silencing Strategies for the Study of Relaxin Family Peptides and Receptors in the Brain.
Dr. Lauren Broom, London, Great Britain: Investigations of the neuroprotective effect of Osteopontin in in vitro and in vivo models of Parkinson's Disease: The role of neurotrophic factors.
Natalie Landeck, BRAINS: Is there a better control for alpha-synuclein?
Dr. Umar M. Sajjad, TNU: Redox dysregulation in Huntington’s disease.
Rana Soylu, TNU: The effects of mutant huntingtin in Sim1 expressing neurons in the hypothalamus.
Fall 2010
Prof. Stephan von Hörsten, Erlangen, Germany: Very early onset andintervention in a pre-HD-syndrome in transgenic mouse and rat models ofHuntington´s disease.
Sanaz Gabery, TNU: Changes in key hypothalamic neuropeptidepopulations in Huntington disease revealed by neuropathologicalanalyses.
Dr. Gurdal Sahin, BRAINS: Evidence for dopamine release from grafted serotonin cells: microdialysis and PET imaging studies.
Helene Hall, BRAINS: Assessment of cholinergic cell loss in Parkinson disease with dementia.
Spring 2010
A/Prof. Anthony Hannan, Melbourne, Australia: Molecular mediators andenvironmental modulators of behavioural endophenotypes in Huntington'sdisease transgenic mice.
Dr. Gurdal Sahin, BRAINS: What Do Basal Ganglia Do? Inspirations from Dr. Marsden.
Dr. Carl Rosenblad, Lund: Clinical Translation of Gene Therapy for Parkinson Disease.
Prof. Freddy Ståhlberg, Lund: Novel advances in MR imaging.
Fall 2009
Dr. Yongxia Zhou, New York, USA: fMRI technique and its application to dementia, aging and memory.
Sara Warsi, BRAINS: Biomedicine project presentation.
Charlotte Sonesson, BRAINS: Early changes in the hypothalamic region in prodromal Huntington disease revealed by MRI analysis.
Sofia Hult and Rana Soylu, TNU: Hypothalamic expression of mutant huntingtin causes metabolic disturbances.
Tomas Björklund, BRAINS: Gene therapy by enzyme replacement for Parkinson’s disease.
Page Manager: Jenny Månsson
Last modified: 2012-05-22
June 4-5
Dr. Jean-Christophe Rochet, Purdue University, West Lafayette, USA, will be visiting us.
