Dermatology and Venereology

Faculty of Medicine | Lund University

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Schmidtchen lab

Bacterial infections spanning from local wound infections, affecting patients with non-healing leg ulcers, postoperative wounds or burns, to severe infections and sepsis, are significant medical problems.

Today's anti-infective treatments do not address the excessive activation of inflammatory pathways during infection and sepsis, and resistance problems are increasing. Hence, there is a huge unmet need for novel therapies that go beyond mere classical antibacterial effects, and which also selectively modulate both pro- and anti-inflammatory pathways during infections.

The purpose of our research is to define and utilize new knowledge on innate immunity, with a focus on endogenous antimicrobial and immunomodulatory peptides and proteins, in order to develop the next generation's anti-infective treatments, with potential applications for skin infections and burns, postoperative profylaxis, but also for invasive infections and sepsis. 

Internships: we have various opportunities for internships throughout the year. Feel free to contact us for further information at mariena.van_der_plas@med.lu.se

artur schmidtchen

Artur Schmidtchen, MD, PhD, Professor
Head, Division of Dermatology and Venereology
Department of Clinical Sciences
Lund University

News

2017-05 New publication by J. Petrlova et al in PNAS:  Aggregation of thrombin-derived C-terminal fragments as a previously undisclosed host defense mechanism. Popular science articles available in Swedish and English

SYMPOSIUM on WOUND HEALING: March 22nd, 2017

2017-02 New publication by S. Eriksson et al in the British Journal of Dermatology: Antibacterial and anti-biofilm effects of sodium hypochlorite against Staphylococcus aureus isolates derived from patients with atopic dermatitis 

2016-12 35,000 SEK grant from stiftelsen Lars Hiertas Minne to Mariena van der Plas

2016-11 Mariena van der Plas received the oral presentation award for her presentation at the joint AWTRS & MEPSA meeting in Melbourne, Australia.

2016-11 80,000 SEK grant from the Royal Physiographic Society to Jitka Petrlova

2016-10 Jitka Petrlova is appointed docent/reader in experimental structural biology at the Medical Faculty of Lund University 

2016-05 New publication by MJAvdP et al in Nature Communications: 'Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses'. For a Swedish popular science article about this study, click here

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