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Publications

Original papers

2011

Ruscher K, Kuric E, Wieloch T. (2011) Levodopa Treatment Improves Functional Recovery After Experimental Stroke. Stroke. 2011 Nov 17. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/22096034

Lobo AC, Gomes JR, Catarino T, Mele M, Fernandez P, Inácio AR, Bahr BA, Santos AE, Wieloch T, Carvalho AL, Duarte CB. (2011) Cleavage of the vesicular glutamate transporters under excitotoxic conditions. Neurobiol Dis. 2011 Dec;44(3):292-303. Epub 2011 Jul 26. http://www.ncbi.nlm.nih.gov/pubmed/21807096

Ng AN, Krogh M, Toresson H. (2011) Dendritic EGFP-STIM1 activation after type I metabotropic glutamate and muscarinic acetylcholine receptor stimulation in hippocampal neuron. J Neurosci Res. 2011 Apr 27. doi: 10.1002/jnr.22648. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/21538465

Kucharz K, Wieloch T, Toresson H. (2011) Potassium-induced structural changes of the endoplasmic reticulum in pyramidal neurons in murine organotypic hippocampal slices. J Neurosci Res. 2011 May 2. doi: 10.1002/jnr.22646. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/21538461

Kucharz K, Wieloch T, Toresson H. (2011) Rapid fragmentation of the endoplasmic reticulum in cortical neurons of the mouse brain in situ following cardiac arrest. J Cereb Blood Flow Metab. 2011 Apr 6. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/21468089

Gomes JR, Lobo AC, Melo CV, Inácio AR, Takano J, Iwata N, Saido TC, de Almeida LP, Wieloch T, Duarte CB. (2011). Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites. J Neurosci. 2011 Mar 23;31(12):4622-35. http://www.ncbi.nlm.nih.gov/pubmed/21430162

Ruscher K, Shamloo M, Rickhag M, Ladunga I, Soriano L, Gisselsson L, Toresson H, Ruslim-Litrus L, Oksenberg D, Urfer R, Johansson BB, Nikolich K, Wieloch T. (2011) The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke. Brain. 2011 Mar;134(Pt 3):732-46. Epub 2011 Jan 28. http://www.ncbi.nlm.nih.gov/pubmed/21278085

2010

Markus T, Hansson SR, Cronberg T, Cilio C, Wieloch T, Ley D. (2010) β-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices. J Neuroinflammation. 2010 Dec 20;7:94.

Hansson MJ, Morota S, Chen L, Matsuyama N, Suzuki Y, Nakajima S, Tanoue T, Omi A, Shibasaki F, Shimazu M, Ikeda Y, Uchino H, Elmér E. (2010) Cyclophilin D-sensitive mitochondrial permeability transition in adult human brain and liver mitochondria. J Neurotrauma. 2010 Dec 1. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/21121808 

Sjovall F, Morota S, Hansson MJ, Friberg H, Gnaiger E, Elmer E. (2010) Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis. Crit Care. 2010 Nov 24;14(6):R214. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/21106065 

Ruscher K, Fernandes E, Capela JP, Bastos MD, Wieloch T, Dirnagl U, Meisel A, Carvalho F.(2010) Effect of 3,4-Methylenedioxyamphetamine on Dendritic Spines Dynamics in Rat Neocortical Neurons - Involvement of Heat Shock Protein 27. Brain Res. 2010 Nov 11. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/21075084 

Inácio AR, Ruscher K, Leng L, Bucala R, Deierborg T. (2010) Macrophage migration inhibitory factor promotes cell death and aggravates neurologic deficits after experimental stroke. J Cereb Blood Flow Metab. 2010 Nov 10. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/21063426 

Tomasevic G, Raghupathi R, Scherbel U, Wieloch T, McIntosh TK. (2010) Deletion of the p53 tumor suppressor gene improves neuromotor function but does not attenuate regional neuronal cell loss following experimental brain trauma in mice. J Neurosci Res. 2010 Oct 1. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/20890990 

Inácio AR, Ruscher K, Wieloch T. (2010) Enriched environment downregulates macrophage migration inhibitory factor and increases parvalbumin in the brain following experimental stroke. Neurobiol Dis. 2010 Sep 27. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/20883785 

Ishizaki T, Erickson A, Kuric E, Shamloo M, Hara-Nishimura I, Inácio AR, Wieloch T, Ruscher K. (2010) The asparaginyl endopeptidase legumain after experimental stroke. J Cereb Blood Flow Metab. 2010 Oct;30(10):1756-66. Epub 2010 Mar 17. http://www.ncbi.nlm.nih.gov/pubmed/20234379 

Månsson R, Morota S, Hansson MJ, Sonoda I, Yasuda Y, Shimazu M, Sugiura A, Yanagi S, Miura H, Uchino H, Elmér E. (2010) Minocycline sensitizes rodent and human liver mitochondria to the permeability transition: implications for toxicity in liver transplantation.  Hepatology. 2010 Jan;51(1):347-8; author reply 349-50. Comment on: Hepatology. 2008 Jan;47(1):236-46. http://www.ncbi.nlm.nih.gov/pubmed/20034033 

Ruscher K, Erickson A, Kuric E, Inácio AR, Wieloch T. (2010) Effects of chronic Clozapine administration on apolipoprotein D levels and on functional recovery following experimental stroke. Brain Res. 2010 Mar 19;1321:152-63. Epub 2010 Jan 18. http://www.ncbi.nlm.nih.gov/pubmed/20083089 

 Gisselsson L, Toresson H, Ruscher K, Wieloch T. (2010). Rho kinase inhibition protects CA1 cells in organotypic hippocampal slices during in vitro ischemia. Brain Res. 2010 Feb 26;1316:92-100. Epub 2009 Dec 22. 
 http://www.ncbi.nlm.nih.gov/pubmed/20026316 
 

Hansson MJ, Morota S, Teilum M, Mattiasson G, Uchino H, Elmer E. (2010) Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume. J Biol Chem. 2010 Jan 1;285(1):741-50. Epub 2009 Oct 30. http://www.ncbi.nlm.nih.gov/pubmed/19880514 

2009

Kucharz, K., Krogh, M., Ng, A. N. and Toresson, H. (2009). NMDA receptor stimulation induces reversible fission of the neuronal endoplasmic reticulum.   PLoS One. 2009;4(4):e5250. Epub 2009 Apr 21. http://www.ncbi.nlm.nih.gov/pubmed/19381304 

Morota S, Månsson R, Hansson MJ, Kasuya K, Shimazu M, Hasegawa E, Yanagi S, Omi A, Uchino H, Elmér E. (2009) Evaluation of putative inhibitors of mitochondrial permeability transition for brain disorders--specificity vs. toxicity. Exp Neurol. 2009 Aug;218(2):353-62. Epub 2009 Apr 5. http://www.ncbi.nlm.nih.gov/pubmed/19348797 

Ruscher K, Johannesson E, Brugiere E, Erickson A, Rickhag M, Wieloch T (2009) Enriched environment reduces apolipoprotein E (ApoE) in reactive astrocytes and attenuates inflammation of the peri-infarct tissue after experimental stroke. J Cereb Blood Flow Metab. 2009 Nov;29(11):1796-805. Epub 2009 Jul 22. http://www.ncbi.nlm.nih.gov/pubmed/19623195 

 2008 

Markus T, Cronberg T, Cilio C, Pronk C, Wieloch T, Ley D. (2009) Tumor necrosis factor receptor-1 is essential for LPS-induced sensitization and tolerance to oxygen-glucose deprivation in murine neonatal organotypic hippocampal slices. J Cereb Blood Flow Metab. 29(1):73-86. Epub 2008 Aug 27. http://www.ncbi.nlm.nih.gov/pubmed/18728678 

Covaciu L, Allers M, Enblad P, Lunderquist A, Wieloch T and Rubertsson S (2008). Intranasal selective brain cooling in pigs Resuscitation 76(1): 83-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17709167 

Deierborg T, Wieloch T, Diano S, Warden CH, Horvath TL and Mattiasson G (2008). Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse J Cereb Blood Flow Metab 28(6): 1186-95 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18301432 

Hansson MJ, Mansson R, Morota S, Uchino H, Kallur T, Sumi T, Ishii N, Shimazu M, Keep MF, Jegorov A and Elmer E (2008). Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition Free Radic Biol Med 45(3): 284-94 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18466779 

Markus T, Cronberg T, Cilio C, Pronk C, Wieloch T and Ley D (2008). Tumor necrosis factor receptor-1 is essential for LPS-induced sensitization and tolerance to oxygen-glucose deprivation in murine neonatal organotypic hippocampal slices J Cereb Blood Flow Metab http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18728678 

Ng AN and Toresson H (2008). Gamma-secretase and metalloproteinase activity regulate the distribution of endoplasmic reticulum to hippocampal neuron dendritic spines Faseb J 22(8): 2832-42 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18424769 

Rickhag M, Deierborg T, Patel S, Ruscher K and Wieloch T (2008). Apolipoprotein D is elevated in oligodendrocytes in the peri-infarct region after experimental stroke: influence of enriched environment J Cereb Blood Flow Metab 28(3): 551-62 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17851453 

Uchino H, Kuroda Y, Morota S, Hirabayashi G, Ishii N, Shibasaki F, Ikeda Y, Hansson MJ and Elmer E (2008). Probing the molecular mechanisms of neuronal degeneration: importance of mitochondrial dysfunction and calcineurin activation J Anesth 22(3): 253-62 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18685932 

 2007 

Månsson R, Hansson MJ, Morota S, Uchino H, Ekdahl CT and Elmér E (2007). Re-evaluation of mitochondrial permeability transition as a primary neuroprotective target of minocycline Neurobiol Dis 25(1): 198-205 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17067803 

Morota S, Hansson MJ, Ishii N, Kudo Y, Elmer E and Uchino H (2007). Spinal cord mitochondria display lower calcium retention capacity compared with brain mitochondria without inherent differences in sensitivity to cyclophilin D inhibition J Neurochem 103(5): 2066-76 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17868326 

Rickhag M, Teilum M and Wieloch T (2007). Rapid and long-term induction of effector immediate early genes (BDNF, Neuritin and Arc) in peri-infarct cortex and dentate gyrus after ischemic injury in rat brain Brain Res 1151: 203-10 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17397810 

Teilum M, Krogh M, Wieloch T and Mattiasson G (2007). Hypothermia affects translocation of numerous cytoplasmic proteins following global cerebral ischemia J Proteome Res 6(7): 2822-32 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17536849 

 2006 

Allers M, Boris-Moller F, Lunderquist A and Wieloch T (2006). A new method of selective, rapid cooling of the brain: an experimental study Cardiovasc Intervent Radiol 29(2): 260-3 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16362468 

Nygren J, Kokaia M and Wieloch T (2006). Decreased expression of brain-derived neurotrophic factor in BDNF(+/-) mice is associated with enhanced recovery of motor performance and increased neuroblast number following experimental stroke J Neurosci Res 84(3): 626-31 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16770774 

Nygren J, Wieloch T, Pesic J, Brundin P and Deierborg T (2006). Enriched environment attenuates cell genesis in subventricular zone after focal ischemia in mice and decreases migration of newborn cells to the striatum Stroke 37(11): 2824-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17008628 

Rickhag M, Wieloch T, Gidö G, Elmér E, Krogh M, Murray J, Lohr S, Bitter H, Chin DJ, von Schack D, Shamloo M and Nikolich K (2006). Comprehensive regional and temporal gene expression profiling of the rat brain during the first 24 h after experimental stroke identifies dynamic ischemia-induced gene expression patterns, and reveals a biphasic activation of genes in surviving tissue J Neurochem 96(1): 14-29 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16300643 

Shamloo M, Soriano L, von Schack D, Rickhag M, Chin DJ, Gonzalez-Zulueta M, Gido G, Urfer R, Wieloch T and Nikolich K (2006). Npas4, a novel helix-loop-helix PAS domain protein, is regulated in response to cerebral ischemia Eur J Neurosci 24(10): 2705-20 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17156197 

Teilum M, Hansson MJ, Dainiak MB, Månsson R, Surve S, Elmér E, Önnerfjord P and Mattiasson G (2006). Binding mitochondria to cryogel monoliths allows detection of proteins specifically released following permeability transition Anal Biochem 348(2): 209-21 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16310157 

 2005 

Cronberg T, Jensen K, Rytter A and Wieloch T (2005). Selective sparing of hippocampal CA3 cells following in vitro ischemia is due to selective inhibition by acidosis Eur J Neurosci 22(2): 310-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16045484 

Cronberg T, Rytter A and Wieloch T (2005). Chelation of intracellular calcium reduces cell death after hyperglycemic in vitro ischemia in murine hippocampal slice cultures Brain Res 1049(1): 120-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15935997 

Gisselsson LL, Matus A and Wieloch T (2005). Actin redistribution underlies the sparing effect of mild hypothermia on dendritic spine morphology after in vitro ischemia J Cereb Blood Flow Metab 25(10): 1346-55 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15874974 

Karlsson J, Petersen A, Gido G, Wieloch T and Brundin P (2005). Combining neuroprotective treatment of embryonic nigral donor tissue with mild hypothermia of the graft recipient Cell Transplant 14(5): 301-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16052911 

Nygren J and Wieloch T (2005). Enriched environment enhances recovery of motor function after focal ischemia in mice, and downregulates the transcription factor NGFI-A J Cereb Blood Flow Metab 25(12): 1625-33 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15917744 

Rytter A, Cardoso CM, Johansson P, Cronberg T, Hansson MJ, Mattiasson G, Elmér E and Wieloch T (2005). The temperature dependence and involvement of mitochondria permeability transition and caspase activation in damage to organotypic hippocampal slices following in vitro ischemia J Neurochem 95(4): 1108-17 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16144540 

Shamloo M, Soriano L, Wieloch T, Nikolich K, Urfer R and Oksenberg D (2005). Death-associated protein kinase is activated by dephosphorylation in response to cerebral ischemia J Biol Chem 280(51): 42290-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16204252 

 2004 

Cronberg T, Rytter A, Asztely F, Soder A and Wieloch T (2004). Glucose but not lactate in combination with acidosis aggravates ischemic neuronal death in vitro Stroke 35(3): 753-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14963271 

Hansson MJ, Månsson R, Mattiasson G, Ohlsson J, Karlsson J, Keep MF and Elmér E (2004). Brain-derived respiring mitochondria exhibit homogeneous, complete and cyclosporin-sensitive permeability transition J Neurochem 89(3): 715-29 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15086528 

Hansson MJ, Mattiasson G, Månsson R, Karlsson J, Keep MF, Waldmeier P, Ruegg UT, Dumont JM, Besseghir K and Elmér E (2004). The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria J Bioenerg Biomembr 36(4): 407-13 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15377880 

Karlsson J, Fong KS, Hansson MJ, Elmér E, Csiszar K and Keep MF (2004). Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis J Neurosurg 101(1): 128-37 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15255263 

Kurihara J, Katsura K, Siesjo BK and Wieloch T (2004). Hyperglycemia and hypercapnia differently affect post-ischemic changes in protein kinases and protein phosphorylation in the rat cingulate cortex Brain Res 995(2): 218-25 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14672811 

Matsumoto S, Shamloo M, Matsumoto E, Isshiki A and Wieloch T (2004). Protein kinase C-gamma and calcium/calmodulin-dependent protein kinase II-alpha are persistently translocated to cell membranes of the rat brain during and after middle cerebral artery occlusion J Cereb Blood Flow Metab 24(1): 54-61 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14688616 

Olsson T, Cronberg T, Rytter A, Asztely F, Fredholm BB, Smith ML and Wieloch T (2004). Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro Eur J Neurosci 20(5): 1197-204 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15341591 

Olsson T, Hansson O, Nylandsted J, Jaattela M, Smith ML and Wieloch T (2004). Lack of neuroprotection by heat shock protein 70 overexpression in a mouse model of global cerebral ischemia Exp Brain Res 154(4): 442-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14579003 

Olsson T, Nygren J, Hakansson K, Lundblad C, Grubb A, Smith ML and Wieloch T (2004). Gene deletion of cystatin C aggravates brain damage following focal ischemia but mitigates the neuronal injury after global ischemia in the mouse Neuroscience 128(1): 65-71 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15450354 

 2003 

Ferrand-Drake M, Zhu C, Gido G, Hansen AJ, Karlsson JO, Bahr BA, Zamzami N, Kroemer G, Chan PH, Wieloch T and Blomgren K (2003). Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia J Neurochem 85(6): 1431-42 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12787063 

Hansson MJ, Persson T, Friberg H, Keep MF, Rees A, Wieloch T and Elmér E (2003). Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria Brain Res 960(1-2): 99-111 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12505662 

Lifshitz J, Friberg H, Neumar RW, Raghupathi R, Welsh FA, Janmey P, Saatman KE, Wieloch T, Grady MS and McIntosh TK (2003). Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus J Cereb Blood Flow Metab 23(2): 219-31 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12571453 

Liu D, Slevin JR, Lu C, Chan SL, Hansson M, Elmér E and Mattson MP (2003). Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death J Neurochem 86(4): 966-79 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12887694 

Macleod MR, Johansson IM, Soderstrom I, Lai M, Gido G, Wieloch T, Seckl JR and Olsson T (2003). Mineralocorticoid receptor expression and increased survival following neuronal injury Eur J Neurosci 17(8): 1549-55 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12752372 

Mattiasson G, Friberg H, Hansson M, Elmér E and Wieloch T (2003). Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation J Neurochem 87(2): 532-44 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14511130 

Mattiasson G, Shamloo M, Gido G, Mathi K, Tomasevic G, Yi S, Warden CH, Castilho RF, Melcher T, Gonzalez-Zulueta M, Nikolich K and Wieloch T (2003). Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma Nat Med 9(8): 1062-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12858170 

Olsson T, Wieloch T and Smith ML (2003). Brain damage in a mouse model of global cerebral ischemia. Effect of NMDA receptor blockade Brain Res 982(2): 260-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12915260 

Rytter A, Cronberg T, Asztely F, Nemali S and Wieloch T (2003). Mouse hippocampal organotypic tissue cultures exposed to in vitro "ischemia" show selective and delayed CA1 damage that is aggravated by glucose J Cereb Blood Flow Metab 23(1): 23-33 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12500088 

 2002 

Friberg H, Wieloch T and Castilho RF (2002). Mitochondrial oxidative stress after global brain ischemia in rats Neurosci Lett 334(2): 111-4 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12435484 

Matsumoto S, Isshiki A, Watanabe Y and Wieloch T (2002). Restricted clinical efficacy of cyclosporin A on rat transient middle cerebral artery occlusion Life Sci 72(4-5): 591-600 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12467900 

Matsumoto S, Shamloo M, Isshiki A and Wieloch T (2002). Persistent phosphorylation of synaptic proteins following middle cerebral artery occlusion J Cereb Blood Flow Metab 22(9): 1107-13 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12218416 

Stenman E, Malmsjo M, Uddman E, Gido G, Wieloch T and Edvinsson L (2002). Cerebral ischemia upregulates vascular endothelin ET(B) receptors in rat Stroke 33(9): 2311-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12215604 

 2001 

Bentzer P, Mattiasson G, McIntosh TK, Wieloch T and Grande PO (2001). Infusion of prostacyclin following experimental brain injury in the rat reduces cortical lesion volume J Neurotrauma 18(3): 275-85 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11284548 

Philips MF, Mattiasson G, Wieloch T, Bjorklund A, Johansson BB, Tomasevic G, Martinez-Serrano A, Lenzlinger PM, Sinson G, Grady MS and McIntosh TK (2001). Neuroprotective and behavioral efficacy of nerve growth factor-transfected hippocampal progenitor cell transplants after experimental traumatic brain injury J Neurosurg 94(5): 765-74 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11354408 

Sakai T, Johnson KJ, Murozono M, Sakai K, Magnuson MA, Wieloch T, Cronberg T, Isshiki A, Erickson HP and Fassler R (2001). Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis Nat Med 7(3): 324-30 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11231631 

 2000 

Gido G, Cronberg T and Wieloch T (2000). The effect of alpha-phenyl-tert-butyl nitrone (PBN) on free radical formation in transient focal ischaemia measured by microdialysis and 3,4-dihydroxybenzoate formation Acta Physiol Scand 168(2): 277-85 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10712565 

Karlsson J, Emgard M, Gido G, Wieloch T and Brundin P (2000). Increased survival of embryonic nigral neurons when grafted to hypothermic rats Neuroreport 11(8): 1665-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10852221 

Mattiasson GJ, Philips MF, Tomasevic G, Johansson BB, Wieloch T and McIntosh TK (2000). The rotating pole test: evaluation of its effectiveness in assessing functional motor deficits following experimental head injury in the rat J Neurosci Methods 95(1): 75-82 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10776817 

Petersen A, Castilho RF, Hansson O, Wieloch T and Brundin P (2000). Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons Brain Res 857(1-2): 20-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10700549 

Shamloo M, Kamme F and Wieloch T (2000). Subcellular distribution and autophosphorylation of calcium/calmodulin-dependent protein kinase II-alpha in rat hippocampus in a model of ischemic tolerance Neuroscience 96(4): 665-74 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10727785 

 1999 

Ferrand-Drake M, Friberg H and Wieloch T (1999). Mitochondrial permeability transition induced DNA-fragmentation in the rat hippocampus following hypoglycemia Neuroscience 90(4): 1325-38 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10338300 

Ferrand-Drake M and Wieloch T (1999). The time-course of DNA fragmentation in the choroid plexus and the CA1 region following transient global ischemia in the rat brain. The effect of intra-ischemic hypothermia Neuroscience 93(2): 537-49 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10465437 

Friberg H, Connern C, Halestrap AP and Wieloch T (1999). Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability J Neurochem 72(6): 2488-97 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10349859 

Katsura K, Kurihara J, Siesjo BK and Wieloch T (1999). Acidosis enhances translocation of protein kinase C but not Ca(2+)/calmodulin-dependent protein kinase II to cell membranes during complete cerebral ischemia Brain Res 849(1-2): 119-27 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10592293 

Khaspekov L, Friberg H, Halestrap A, Viktorov I and Wieloch T (1999). Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons Eur J Neurosci 11(9): 3194-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10510183 

Laake JH, Haug FM, Wieloch T and Ottersen OP (1999). A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence Brain Res Brain Res Protoc 4(2): 173-84 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10446412 

Matsumoto S, Friberg H, Ferrand-Drake M and Wieloch T (1999). Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion J Cereb Blood Flow Metab 19(7): 736-41 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10413027 

Olsson T, Johansson IM, Dahlqvist P, Ronnback A, Wieloch T and Johansson B (1999). Glucocorticoid axis abnormalities related to brain damage Acta Physiol Scand 167(2): A9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10571563 

Shamloo M, Rytter A and Wieloch T (1999). Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning Neuroscience 93(1): 81-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10430472 

Shamloo M and Wieloch T (1999). Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic tolerance J Cereb Blood Flow Metab 19(2): 173-83 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10027773 

Shamloo M and Wieloch T (1999). Rapid decline in protein kinase Cgamma levels in the synaptosomal fraction of rat hippocampus after ischemic preconditioning Neuroreport 10(5): 931-5 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10321462 

Tomasevic G, Kamme F, Stubberod P, Wieloch M and Wieloch T (1999). The tumor suppressor p53 and its response gene p21WAF1/Cip1 are not markers of neuronal death following transient global cerebral ischemia Neuroscience 90(3): 781-92 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10218779 

Tomasevic G, Shamloo M, Israeli D and Wieloch T (1999). Activation of p53 and its target genes p21(WAF1/Cip1) and PAG608/Wig-1 in ischemic preconditioning Brain Res Mol Brain Res 70(2): 304-13 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10407180 

 1998 

Boris-Moller F, Kamme F and Wieloch T (1998). The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat Brain Res Mol Brain Res 63(1): 163-73 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9838092 

Boris-Moller F and Wieloch T (1998). Changes in the extracellular levels of glutamate and aspartate during ischemia and hypoglycemia. Effects of hypothermia Exp Brain Res 121(3): 277-84 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9746134 

Boris-Moller F and Wieloch T (1998). The effect of 4 beta-phorbol-12,13-dibutyrate and staurosporine on the extracellular glutamate levels during ischemia in the rat striatum Mol Chem Neuropathol 35(1-3): 133-47 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10343975 

Cardell M, Landsend AS, Eidet J, Wieloch T, Blackstad TW and Ottersen OP (1998). High resolution immunogold analysis reveals distinct subcellular compartmentation of protein kinase C gamma and delta in rat Purkinje cells Neuroscience 82(3): 709-25 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9483530 

Friberg H, Ferrand-Drake M, Bengtsson F, Halestrap AP and Wieloch T (1998). Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death J Neurosci 18(14): 5151-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9651198 

Khaspekov L, Shamloo M, Victorov I and Wieloch T (1998). Sublethal in vitro glucose-oxygen deprivation protects cultured hippocampal neurons against a subsequent severe insult Neuroreport 9(7): 1273-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9631411 

Runden E, Seglen PO, Haug FM, Ottersen OP, Wieloch T, Shamloo M and Laake JH (1998). Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism J Neurosci 18(18): 7296-305 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9736650 

Tomasevic G, Kamme F and Wieloch T (1998). Changes in proliferating cell nuclear antigen, a protein involved in DNA repair, in vulnerable hippocampal neurons following global cerebral ischemia Brain Res Mol Brain Res 60(2): 168-76 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9757027 

Uchino H, Elmér E, Uchino K, Li PA, He QP, Smith ML and Siesjö BK (1998). Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat Brain Res 812(1-2): 216-26 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9813336 

 1996 

Coimbra C, Boris-Moller F, Drake M and Wieloch T (1996). Diminished neuronal damage in the rat brain by late treatment with the antipyretic drug dipyrone or cooling following cerebral ischemia Acta Neuropathol 92(5): 447-53 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8922055 

Coimbra C, Drake M, Boris-Moller F and Wieloch T (1996). Long-lasting neuroprotective effect of postischemic hypothermia and treatment with an anti-inflammatory/antipyretic drug. Evidence for chronic encephalopathic processes following ischemia Stroke 27(9): 1578-85 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8784133 

Drake M, Friberg H, Boris-Moller F, Sakata K and Wieloch T (1996). The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain Acta Physiol Scand 158(2): 155-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8899062 

Kamme F and Wieloch T (1996). Induction of junD mRNA after transient forebrain ischemia in the rat. Effect of hypothermia Brain Res Mol Brain Res 43(1-2): 51-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9037518 

Kamme F and Wieloch T (1996). The effect of hypothermia on protein synthesis and the expression of immediate early genes following transient cerebral ischemia Adv Neurol 71: 199-206; discussion 206-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8790800 

Nilsson OG, Saveland H, Boris-Moller F, Brandt L and Wieloch T (1996). Increased levels of glutamate in patients with subarachnoid haemorrhage as measured by intracerebral microdialysis Acta Neurochir Suppl 67: 45-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8870801 

Saveland H, Nilsson OG, Boris-Moller F, Wieloch T and Brandt L (1996). Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage Neurosurgery 38(1): 12-9; discussion 19-20 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8747946 

Wieloch T, Hu BR, Boris-Moller A, Cardell M, Kamme F, Kurihara J and Sakata K (1996). Intracellular signal transduction in the postischemic brain Adv Neurol 71: 371-87; discussion 387-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8790813 

 1995 

Hu BR, Kamme F and Wieloch T (1995). Alterations of Ca2+/calmodulin-dependent protein kinase II and its messenger RNA in the rat hippocampus following normo- and hypothermic ischemia Neuroscience 68(4): 1003-16 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8544977 

Hu BR, Kurihara J and Wieloch T (1995). Persistent translocation and inhibition of Ca2+/calmodulin-dependent protein kinase II in the crude synaptosomal fraction of the vulnerable hippocampus following hypoglycemia J Neurochem 64(3): 1361-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7861169 

Hu BR and Wieloch T (1995). Persistent translocation of Ca2+/calmodulin-dependent protein kinase II to synaptic junctions in the vulnerable hippocampal CA1 region following transient ischemia J Neurochem 64(1): 277-84 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7798923 

Kamme F, Campbell K and Wieloch T (1995). Biphasic expression of the fos and jun families of transcription factors following transient forebrain ischaemia in the rat. Effect of hypothermia Eur J Neurosci 7(10): 2007-16 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8542058 

 1994 

Coimbra C and Wieloch T (1994). Moderate hypothermia mitigates neuronal damage in the rat brain when initiated several hours following transient cerebral ischemia Acta Neuropathol 87(4): 325-31 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8017166 

Hu BR and Wieloch T (1994). Tyrosine phosphorylation and activation of mitogen-activated protein kinase in the rat brain following transient cerebral ischemia J Neurochem 62(4): 1357-67 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7510779 

Kurihara J, Hu BR and Wieloch T (1994). Changes in the tyrosine phosphorylation of mitogen-activated protein kinase in the rat hippocampus during and following severe hypoglycemia J Neurochem 63(6): 2346-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7525877 

 1993 

Anderson KJ, Nellgard B and Wieloch T (1993). Ischemia-induced upregulation of excitatory amino acid transport sites Brain Res 622(1-2): 93-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7902192 

Bergstedt K, Hu BR and Wieloch T (1993). Initiation of protein synthesis and heat-shock protein-72 expression in the rat brain following severe insulin-induced hypoglycemia Acta Neuropathol 86(2): 145-53 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8213069 

Bergstedt K, Hu BR and Wieloch T (1993). Postischaemic changes in protein synthesis in the rat brain: effects of hypothermia Exp Brain Res 95(1): 91-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8405256 

Bergstedt K and Wieloch T (1993). Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat. Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1 J Cereb Blood Flow Metab 13(5): 895-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8360296 

Cardell M and Wieloch T (1993). Time course of the translocation and inhibition of protein kinase C during complete cerebral ischemia in the rat J Neurochem 61(4): 1308-14 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8376989 

Hu BR and Wieloch T (1993). Casein kinase II activity in the postischemic rat brain increases in brain regions resistant to ischemia and decreases in vulnerable areas J Neurochem 60(5): 1722-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8473892 

Hu BR and Wieloch T (1993). Changes in tyrosine phosphorylation in neocortex following transient cerebral ischaemia Neuroreport 4(2): 219-22 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7680914 

Hu BR and Wieloch T (1993). Stress-induced inhibition of protein synthesis initiation: modulation of initiation factor 2 and guanine nucleotide exchange factor activities following transient cerebral ischemia in the rat J Neurosci 13(5): 1830-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8478677 

Hu BR, Yang YB and Wieloch T (1993). Depression of neuronal protein synthesis initiation by protein tyrosine kinase inhibitors J Neurochem 61(5): 1789-94 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8228995 

Hu BR, Yang YB and Wieloch T (1993). Heat-shock inhibits protein synthesis and eIF-2 activity in cultured cortical neurons Neurochem Res 18(9): 1003-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8232716 

Wieloch T, Bergstedt K and Hu BR (1993). Protein phosphorylation and the regulation of mRNA translation following cerebral ischemia Prog Brain Res 96: 179-91 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8332740 

 1992 

Coimbra C and Wieloch T (1992). Hypothermia ameliorates neuronal survival when induced 2 hours after ischaemia in the rat Acta Physiol Scand 146(4): 543-4 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1492573 

Deshpande J, Bergstedt K, Linden T, Kalimo H and Wieloch T (1992). Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: evidence against programmed cell death Exp Brain Res 88(1): 91-105 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1371756 

Gustafson I, Liden A and Wieloch T (1992). Brain cortical tissue levels of noradrenaline and its glycol metabolites: effects of ischemia and postischemic administration of idazoxan Exp Brain Res 90(3): 551-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1358670 

Gustafson I, Westerberg EJ and Wieloch T (1992). Effects of ischemia on regional ligand binding to adrenoceptors in the rat brain J Neurol Sci 113(2): 165-76 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1362586 

Nellgard B and Wieloch T (1992). Cerebral protection by AMPA- and NMDA-receptor antagonists administered after severe insulin-induced hypoglycemia Exp Brain Res 92(2): 259-66 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1362958 

Nellgard B and Wieloch T (1992). NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain Acta Physiol Scand 146(4): 497-503 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1283483 

Nellgard B and Wieloch T (1992). Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia J Cereb Blood Flow Metab 12(1): 2-11 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1345757 

 1991 

Cardell M, Boris-Moller F and Wieloch T (1991). Hypothermia prevents the ischemia-induced translocation and inhibition of protein kinase C in the rat striatum J Neurochem 57(5): 1814-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1919586 

Cardell M, Siesjo BK and Wieloch T (1991). Changes in pyruvate dehydrogenase complex activity during and following severe insulin-induced hypoglycemia J Cereb Blood Flow Metab 11(1): 122-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1983996 

Gustafson I, Westerberg EJ and Wieloch T (1991). Extracellular brain cortical levels of noradrenaline in ischemia: effects of desipramine and postischemic administration of idazoxan Exp Brain Res 86(3): 555-61 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1684752 

Nellgard B, Gustafson I and Wieloch T (1991). Lack of protection by the N-methyl-D-aspartate receptor blocker dizocilpine (MK-801) after transient severe cerebral ischemia in the rat Anesthesiology 75(2): 279-287 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1859015 

Saitoh T, Masliah E, Jin LW, Cole GM, Wieloch T and Shapiro IP (1991). Protein kinases and phosphorylation in neurologic disorders and cell death Lab Invest 64(5): 596-616 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2030574 

Wieloch T, Cardell M, Bingren H, Zivin J and Saitoh T (1991). Changes in the activity of protein kinase C and the differential subcellular redistribution of its isozymes in the rat striatum during and following transient forebrain ischemia J Neurochem 56(4): 1227-35 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2002338 

 1990 

Cardell M, Bingren H, Wieloch T, Zivin J and Saitoh T (1990). Protein kinase C is translocated to cell membranes during cerebral ischemia Neurosci Lett 119(2): 228-32 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2280899 

Gustafson I, Westerberg E and Wieloch T (1990). Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: influence of time of administration and possible mechanisms of action J Cereb Blood Flow Metab 10(6): 885-94 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1976642 

Lauritzen M, Hansen AJ, Kronborg D and Wieloch T (1990). Cortical spreading depression is associated with arachidonic acid accumulation and preservation of energy charge J Cereb Blood Flow Metab 10(1): 115-22 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2105327 

Lundgren J, Cardell M, Wieloch T and Siesjo BK (1990). Preischemic hyperglycemia and postischemic alteration of rat brain pyruvate dehydrogenase activity J Cereb Blood Flow Metab 10(4): 536-41 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2347883 

Westerberg E, Magnusson K, Wieloch T, Ungerstedt U, Speciale C and Schwarcz R (1990). Extracellular levels of quinolinic acid are moderately increased in rat neostriatum following severe insulin-induced hypoglycaemia Acta Physiol Scand 138(3): 417-22 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2139298 

Wieloch T, Miyauchi Y and Lindvall O (1990). Neuronal damage in the striatum following forebrain ischemia: lack of effect of selective lesions of mesostriatal dopamine neurons Exp Brain Res 83(1): 159-63 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2073936 

Zhang ET, Hansen AJ, Wieloch T and Lauritzen M (1990). Influence of MK-801 on brain extracellular calcium and potassium activities in severe hypoglycemia J Cereb Blood Flow Metab 10(1): 136-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2404997 

 1989 

Cardell M, Koide T and Wieloch T (1989). Pyruvate dehydrogenase activity in the rat cerebral cortex following cerebral ischemia J Cereb Blood Flow Metab 9(3): 350-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2715207 

Gustafson I, Miyauchi Y and Wieloch TW (1989). Postischemic administration of idazoxan, an alpha-2 adrenergic receptor antagonist, decreases neuronal damage in the rat brain J Cereb Blood Flow Metab 9(2): 171-4 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2564004 

Hardebo JE, Wieloch T and Kahrstrom J (1989). Excitatory amino acids and cerebrovascular tone Acta Physiol Scand 136(3): 483-5 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2546374 

Magnusson K and Wieloch T (1989). Impairment of protein ubiquitination may cause delayed neuronal death Neurosci Lett 96(3): 264-70 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2541380 

Miyauchi Y, Wieloch T and Lindvall O (1989). Noradrenaline metabolism in neocortex and hippocampus following transient forebrain ischemia in rats: relation to development of selective neuronal necrosis J Neurochem 53(2): 408-15 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2501451 

Westerberg E, Monaghan DT, Kalimo H, Cotman CW and Wieloch TW (1989). Dynamic changes of excitatory amino acid receptors in the rat hippocampus following transient cerebral ischemia J Neurosci 9(3): 798-805 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2538582 

Westerberg E and Wieloch TW (1989). Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia J Neurochem 52(5): 1340-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2565371 

 1988 

Westerberg E, Kehr J, Ungerstedt U and Wieloch T (1988). The Nmda-Antagonist Mk-801 Reduces Extracellular Amino-Acid Levels during Hypoglycemia and Prevent Striatal Damage Neuroscience Research Communications 3(3): 151-158 http://apps.isiknowledge.com/InboundService.do?product=WOS&action=retrieve&SrcApp=EndNote&UT=A1988R095300004&SID=R1ebHEbabcg7KbNGOf%40&SrcAuth=ResearchSoft&mode=FullRecord&customersID=ResearchSoft&DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html 

 1987 

Deshpande JK, Siesjo BK and Wieloch T (1987). Calcium accumulation and neuronal damage in the rat hippocampus following cerebral ischemia J Cereb Blood Flow Metab 7(1): 89-95 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3805166 

Linden T, Kalimo H and Wieloch T (1987). Protective effect of lesion to the glutamatergic cortico-striatal projections on the hypoglycemic nerve cell injury in rat striatum Acta Neuropathol 74(4): 335-44 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3687385 

Westerberg E, Deshpande JK and Wieloch T (1987). Regional differences in arachidonic acid release in rat hippocampal CA1 and CA3 regions during cerebral ischemia J Cereb Blood Flow Metab 7(2): 189-92 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3104354 

Westerberg E, Monaghan DT, Cotman CW and Wieloch T (1987). Excitatory amino acid receptors and ischemic brain damage in the rat Neurosci Lett 73(2): 119-24 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2881232 

 1986 

Deshpande JK and Wieloch T (1986). Flunarizine, a calcium entry blocker, ameliorates ischemic brain damage in the rat Anesthesiology 64(2): 215-24 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3946808 

Engelsen B, Westerberg E, Fonnum F and Wieloch T (1986). Effect of insulin-induced hypoglycemia on the concentrations of glutamate and related amino acids and energy metabolites in the intact and decorticated rat neostriatum J Neurochem 47(5): 1634-41 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2876060 

Koide T, Wieloch TW and Siesjo BK (1986). Chronic dexamethasone pretreatment aggravates ischemic neuronal necrosis J Cereb Blood Flow Metab 6(4): 395-404 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3090061 

Koide T, Wieloch TW and Siesjo BK (1986). Circulating catecholamines modulate ischemic brain damage J Cereb Blood Flow Metab 6(5): 559-65 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2876001 

Siesjo BK, Ingvar M and Wieloch T (1986). Cellular and molecular events underlying epileptic brain damage Ann N Y Acad Sci 462: 207-23 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2871793 

Siesjo BK, Martin I and Wieloch T (1986). Cellular and Molecular Events Underlying Epileptic Brain Damagea Annals of the New York Academy of Sciences 462(Electroconvulsive Therapy: Clinical and Basic Research Issues): 207-223 http://dx.doi.org/10.1111/j.1749-6632.1986.tb51255.x 

Siesjo BK and Wieloch T (1986). Epileptic brain damage: pathophysiology and neurochemical pathology Adv Neurol 44: 813-47 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2871725 

Warner DS, Deshpande JK and Wieloch T (1986). The effect of isoflurane on neuronal necrosis following near-complete forebrain ischemia in the rat Anesthesiology 64(1): 19-23 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3942333 

Westerberg E and Wieloch T (1986). Lesions to the corticostriatal pathways ameliorate hypoglycemia-induced arachidonic acid release J Neurochem 47(5): 1507-11 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3093637 

Wieloch T (1986). Endogenous excitotoxins as possible mediators of ischemic and hypoglycemic brain damage Adv Exp Med Biol 203: 127-38 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2878560 

 1985 

Auer R, Kalimo H, Olsson Y and Wieloch T (1985). The dentate gyrus in hypoglycemia: pathology implicating excitotoxin-mediated neuronal necrosis Acta Neuropathol 67(3-4): 279-88 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4050343 

Blomqvist P, Lindvall O, Stenevi U and Wieloch T (1985). Cyclic AMP concentrations in rat neocortex and hippocampus during and following incomplete ischemia: effects of central noradrenergic neurons, prostaglandins, and adenosine J Neurochem 44(5): 1345-53 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2985751 

Blomqvist P, Lindvall O and Wieloch T (1985). Lesions of the locus coeruleus system aggravate ischemic damage in the rat brain Neurosci Lett 58(3): 353-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4047495 

Blomqvist P and Wieloch T (1985). Ischemic brain damage in rats following cardiac arrest using a long-term recovery model J Cereb Blood Flow Metab 5(3): 420-31 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4030919 

Deshpande JK and Wieloch T (1985). Amelioration of ischaemic brain damage by postischaemic treatment with flunarizine Neurol Res 7(1): 27-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2860585 

Fredriksson K, Rosen I, Johansson BB and Wieloch T (1985). Cerebral platelet thromboembolism and thromboxane synthetase inhibition Stroke 16(5): 800-5 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2996185 

Siesjo BK, Bendek G, Koide T, Westerberg E and Wieloch T (1985). Influence of acidosis on lipid peroxidation in brain tissues in vitro J Cereb Blood Flow Metab 5(2): 253-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3988824 

Siesjo BK and Wieloch T (1985). Cerebral metabolism in ischaemia: neurochemical basis for therapy Br J Anaesth 57(1): 47-62 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3917676 

Tossman U, Wieloch T and Ungerstedt U (1985). gamma-Aminobutyric acid and taurine release in the striatum of the rat during hypoglycemic coma, studied by microdialysis Neurosci Lett 62(2): 231-5 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4088534 

Wieloch T (1985). Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist Science 230(4726): 681-3 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2996146 

Wieloch T (1985). Neurochemical correlates to selective neuronal vulnerability Prog Brain Res 63: 69-85 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2872696 

Wieloch T (1985). Trypsin activation of porcine procolipase. Kinetics of activation and effects on lipid binding FEBS Lett 185(1): 63-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3838943 

Wieloch T, Engelsen B, Westerberg E and Auer R (1985). Lesions of the glutamatergic cortico-striatal projections in the rat ameliorate hypoglycemic brain damage in the striatum Neurosci Lett 58(1): 25-30 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2864666 

Wieloch T, Lindvall O, Blomqvist P and Gage FH (1985). Evidence for amelioration of ischaemic neuronal damage in the hippocampal formation by lesions of the perforant path Neurol Res 7(1): 24-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2860584 

 1984 

Auer RN, Wieloch T, Olsson Y and Siesjo BK (1984). The distribution of hypoglycemic brain damage Acta Neuropathol 64(3): 177-91 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6496035 

Blomqvist P, Lindvall O and Wieloch T (1984). Delayed postischemic hypoperfusion: evidence against involvement of the noradrenergic locus ceruleus system J Cereb Blood Flow Metab 4(3): 425-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6432810 

Drakenberg T, Andersson T, Forsen S and Wieloch T (1984). Calcium ion binding to pancreatic phospholipase A2 and its zymogen: a 43Ca NMR study Biochemistry 23(11): 2387-92 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6477872 

Harris RJ, Wieloch T, Symon L and Siesjo BK (1984). Cerebral extracellular calcium activity in severe hypoglycemia: relation to extracellular potassium and energy state J Cereb Blood Flow Metab 4(2): 187-93 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6725431 

Hougaard K, Ingvar M, Wieloch T and Siesjo BK (1984). Cerebral metabolic and circulatory effects of 1,1,1-trichloroethane, a neurotoxic industrial solvent. 1. Effects on local cerebral glucose consumption and blood flow during acute exposure Neurochem Pathol 2(1): 39-53 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6536881 

Smith ML, Bendek G, Dahlgren N, Rosen I, Wieloch T and Siesjo BK (1984). Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model Acta Neurol Scand 69(6): 385-401 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6464670 

Wieloch T, Harris RJ, Symon L and Siesjo BK (1984). Influence of severe hypoglycemia on brain extracellular calcium and potassium activities, energy, and phospholipid metabolism J Neurochem 43(1): 160-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6726243 

 1983 

Hougaard K, Nilsson B and Wieloch T (1983). Fatty acid cyclo-oxygenase inhibitors and the regulation of cerebral blood flow Acta Physiol Scand 117(4): 585-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6410688 

 1982 

Wieloch T, Harris RJ and Siesjo BK (1982). Brain metabolism and ischemia: mechanism of cell damage and principles of protection J Cereb Blood Flow Metab 2 Suppl 1: S5-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7085798 

Reviews, book chapters and other publications

 2008 

Endres M, Engelhardt B, Koistinaho J, Lindvall O, Meairs S, Mohr JP, Planas A, Rothwell N, Schwaninger M, Schwab ME, Vivien D, Wieloch T and Dirnagl U (2008). Improving outcome after stroke: overcoming the translational roadblock. In: Cerebrovasc Dis. 25: 268-78 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18292653 

 2007 

Wieloch T, Mattiasson G, Hansson M and Elmér E (2007). Mitochondrial Permeability Transition in the CNS - Composition, Regulation, and Pathophysiological Relevance. In: Handbook of Neurochemistry and Molecular Neurobiology. Brain Energetics: Integration of Molecular and Cellular Processes. G. E. Gibson and G. A. Dienel. Berlin Heidelberg, Springer-Verlag. 5: 667-702 2006 Brundin P, Angela Cenci M and Wieloch T (2006). On the move to stimulate cell plasticity in the substantia nigra in Parkinson's disease. In: Exp Neurol. 201: 1-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16806183 

Wieloch T and Nikolich K (2006). Mechanisms of neural plasticity following brain injury. In: Curr Opin Neurobiol. 16: 258-64 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16713245 

 2004 

Friberg H, Herlitz J, Rubertsson S and Wieloch T (2004). Therapeutic hypothermia after cardiac arrest - a new link in the chain can save life, in Swedish. Lakartidningen. 101: 2412-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15314937 

Lifshitz J, Sullivan PG, Hovda DA, Wieloch T and McIntosh TK (2004). Mitochondrial damage and dysfunction in traumatic brain injury. In: Mitochondrion. 4: 705-13 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16120426 

 2003 

Keep MF, Fong KSK, Csiszar K and Elmér E (2003). Cyclosporin A prolongs survival of SOD1 mutant mice and implicates mitochondrial permeability transition in amyotrophic lateral sclerosis. In: Immunosuppressant analogs in neuroprotection. C. V. Borlongan, O. Isacson and P. R. Sanberg. Totowa, Humana Press: 343-359 Keep MF, Uchino H and Elmér E (2003). Introduction: Immunosuppressants as neuroprotective agents. In: Immunosuppressant analogs in neuroprotection. C. V. Borlongan, O. Isacson and P. R. Sanberg. Totowa, Humana Press: 3-32

 2002 

Friberg H and Wieloch T (2002). Mitochondrial permeability transition in acute neurodegeneration. In: Biochimie. 84: 241-50 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12022955 

Wieloch T (2002). Mechanisms of ischemic brain damage. In: Cerebral Blood Flow and Metabolism. L. Edvinsson and D. Krause. NY, USA, Lippincott: 423-451

 2001 

Wieloch T (2001). Mitochondrial involvement in acute neurodegeneration. In: IUBMB Life. 52: 247-54 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11798039 

Wieloch T and Boris-Moller F (2001). High time to test hypothermia in the treatment of stroke, in Swedish Lakartidningen. 98: 2172-5 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11402595 

 1998 

McIntosh TK, Juhler M and Wieloch T (1998). Novel pharmacologic strategies in the treatment of experimental traumatic brain injury: 1998. In: J Neurotrauma. 15: 731-69 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9814632 

Wieloch T, Hu BR and Shamloo M (1998). Cell signaling following ischemia. In: Frontiers in Cerebrovascular Disease: Mechanisms, Diagnosis and Treatment. J. T. Robertsson and T. Nowak, Futura Publishing Company: 139-147

Wieloch T and Kamme F (1998). Cell signaling and ischemic neuronal death. In: Cerebrovascular Disease M. D. Ginsberg and J. Bogousslavsky, Blackwell: 440 - 454

 1997 

Shamloo M and Wieloch T (1997). Preconditioning depresses excitatory cell signalling following the second lethal insult. In: The maturation phenomenon in cerebral ischemia II. U. Ito and I. Klatzo: 77-84

Tomasevic G, Stubberod P, Wieloch M and Wieloch T (1997). DNA damage and repair. Changes in the tumor suppressor protein p53 and the proliferative nuclear antigen (PCNA) in the rat brain following transiewnt cerebral ischemia. In: Pharmacology of cerebral ischemia. J. Krigelstein: 85-89

 1996 

Wieloch T, Hu BR, BorisMoller A, Cardell M, Kamme F, Kurihara J and Sakata K (1996). Intracellular signal transduction in the postischemic brain. In: Cellular and Molecular Mechanisms of Ischemic Brain Damage, Siesjo, B. K. Wieloch, T. 71: 371-388 http://apps.isiknowledge.com/InboundService.do?product=WOS&action=retrieve&SrcApp=EndNote&UT=A1996BG71K00028&SID=R1ebHEbabcg7KbNGOf%40&SrcAuth=ResearchSoft&mode=FullRecord&customersID=ResearchSoft&DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html 

 1993 

Wieloch T, Bergstedt K and Hu BR (1993). Protein-Phosphorylation and the Regulation of Messenger-Rna Translation Following Cerebral-Ischemia. In: Progress in Brain Research. 96: 179-191 http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=A1993LF83200012&SID=R1ebHEbabcg7KbNGOf%40&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord&customersID=ResearchSoft&DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html 

 1992 

Wieloch T, Bergstedt K, Bingren H, Cardell M, Gustafson I, Honoré B, Nellgard B and Westerberg E (1992). The importance of postischemic neurotransmission for delayed neuronal death. In: Maturation phenomenon in cerebral ischemia. U. Ito, T. Kirino, T. Kuroiwa and I. Klatzo, Springer: 107-121

 1991 

Saitoh T, Masliah E, Jin LW, Cole GM, Wieloch T and Shapiro IP (1991). Protein-Kinases and Phosphorylation in Neurologic Disorders and Cell-Death. In: Laboratory Investigation. 64: 596-616 http://apps.isiknowledge.com/InboundService.do?product=WOS&action=retrieve&SrcApp=EndNote&UT=A1991FM28000002&SID=R1ebHEbabcg7KbNGOf%40&SrcAuth=ResearchSoft&mode=FullRecord&customersID=ResearchSoft&DestFail=http%3A%2F%2Fwww.isinet.com%2Fisi%2Fproducts%2Fesource%2Fservice.html#output_options 

Wieloch T (1991). Glutamate neurotoxicity and ischemic neuronal damage. In: Advances in Brain Resuscitation. H. Takeshita, B. K. Siesjö and J. D. Miller, Springer Verlag: 21-43 Wieloch T (1991). Neuronal injury and cerebrovascular disorders In: Curr Opinion in Neurology & Neurosurgery. 3: 944-950

 1989 

Benveniste H, Joregensen M, Lauritzen M, Lundbaeck JA, Zhang ET, Wieloch T and Hansen AJ (1989). The role of glutamate receptors for calcium entry in hippocampal neurons during ischemia. In: Pharmacology of cerebral ischemia. J. Krieglstein, CRC Press: 181-186

Gustafson I, Miyauchi Y and Wieloch T (1989). Modulation of ischemic damage by noradrenaline. Protection by idazoxan, an alpha-2-receptor antagonist. In: Cerebrovascular Disease. M. Ginsberg and D. Dietrich, Raven Press: 117-121

Wieloch T, Cardell M, Saitoh T and Zivin J (1989). Protein kinase C is translocated to the plasma membrane during cerebral ischemia, but partially inactivated. In: Neurotransmission and cerebro-vascular function. J. Seylaz and R. Sercombe, Elsevier Science publishers B.V: 481-484

Zhang ET, Lauritzen M, Wieloch T and Hansen AJ (1989). Calcium movements in brain during failure of energy metabolism. In: Cerebral ischemia and calcium. A. Hartmann and W. Kuchinsky, Springer-Verlag: 162-168

 1988 

Hansen AJ, Lauritzen M and Wieloch T (1988). NMDA antagonists inhibit cortical spreading depression but not anoxic depolarisation. In: Frontiers in excitatory amino acid research. New York, Alan Liss Inc: 661-666

Magnuson K, Gustafson I, Westerberg E and Wieloch T (1988). Neurotransmitter modulation of neuronal damage following cerebral ischemia: Effects on protein ubiquitination. In: Mechanisms of cerebral hypoxia and stroke. G. Somjen, Plenum: 309-319

Westerberg E and Wieloch T (1988). Excitatory amino acid receptors and hypoglycemic brain damage. In: Frontiers in excitatory amino acid research. New York, Alan Liss Inc: 645-652

Wieloch T, Gustafson I and Westerberg E (1988). Effects of the non-competitive NMDA-receptor antagonist MK-801 on ischemic and hypoglycemic brain damage. In: Frontiers in excitatory amino acid research. New York, Alan Liss Inc: 715-722

 1987 

Wieloch T and Westerberg E (1987). Excitatory amino acids and hypoglycemic brain damage. In: Excitatory amino acid transmission. D. Lodge and R. Hirs. New York, Alan Liss Inc: 225-232

 1986 

Wieloch T (1986). Endogenous excitotoxins as possible mediators of ischemic and hypoglycemic brain damage. In: Excitatory amino acids and epilepsy. R. Schwarcz and Y. Ben Ari, Raven Press: 127-139

Wieloch T, Auer R, Westerberg E, Tossman U and Ungerstedt U (1986). Hypoglycemic brain damage is mediated by excitotoxins. In: Excitatory amino acids. P. Roberts, McMillan Press: 482-485

Wieloch T, Koide T and Westerberg E (1986). Inhibitory neurotranmsitters and neuromodulators as protective agents against ischemic brain damage. In: The pharmacology of ischemic brain damage K. Krieglstein. Amsterdam, Elsevier 191-197

 1985 

Siesjo BK and Wieloch T (1985). Brain injury: Neurochemical aspects. In: Central Nervous System Trauma-status report. Becker and Povlischock, William Byrd Press Inc.: 513-532

Siesjo BK and Wieloch T (1985). Epileptic brain damage: Pathophysiology and neurochemical pathology. In: Advances in Neurology Delgado-Escueta, Ward and Woodbury. NY, USA, Raven Press William Byrd Press. 44: 813-847

Siesjo BK and Wieloch T (1985). Molecular mechanisms of ischemic brain damage: Calcium related events. In: Cerebrovascular diseases. F. Plum and W. Pulsinelli. NY, USA, Raven Press: 187-200

 1983 

Siesjo BK and Wieloch T (1983). Fatty Acid Metabolims and mechanisms of ischemic brain damage in cerebrovascular diseases. In: Cerebrovascular diseases. M. Reivich and H. I. Hurting. NY, USA, Raven Press: 251-268

Siesjo BK and Wieloch T (1983). Prostaglandins and the cerebral circulation. In: Adv Prostaglandin Thromboxane Leukot Res. B. Samuelsson, R. Paloetti and P. Ramwell. NY, USA, Raven Press. 12: 339-44 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6221611 

 1982 

Wieloch T and Siesjo BK (1982). Ischemic brain injury: the importance of calcium, lipolytic activities and free fatty acids In: Pathol Biol (Paris) 30(5): 269-77 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7048218 


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