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Potential new stroke therapy discovered at Lab ExpBr

2011-06-16

In a recent article in the journal Brain researchers at the LabExpBr together with American collegues describe a finding that potentially may become a stroke treatment.

The Sigma-1 receptor was identified as a protein upregulated in conditions of improved brain function. Its ligand, SA4503, given to rats as late as 2 days after stroke, significantly improved neurological function. Also the activation of the Sigma-1 receptor enhanced neurite outgrowth and molecular trafficking in astrocytes.

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Last modified: 2011-06-16