The Öresund Cardiovascular Research Collaboration - ÖCRC

The Öresund Cardiovascular Research Collaboration was initiated in 2010 by Göran Rådegran to facilitate and promote research collaborations in the Öresund region, between Skåne University hospital and Lund University with CMRC, Rigshospitalet and Copenhagen University. Interdisciplinary research are planned to be performed in a translational manner from animals, to healthy humans and patients with cardiovascular and pulmonary disorders. The research is focused on the control of vascular tone in the pulmonary circulation, skeletal and cardiac muscle, during rest and exercise, in normoxia and hypoxia, in health and disease.

Selected ongoing projects

1. Role of P2Y1 and P2Y12 receptors in hypoxic pulmonary vasoconstriction

- David Kylhammar, Laurids Bune and Göran Rådegran

2. Role of Thromboxane A2 and COX-2 in hypoxic pulmonary vasoconstriction

- David Kylhammar and Göran Rådegran

3. Role of ET in hypoxic pulmonary vasoconstriction pig

- Petter Hedelin, David Kylhammar and Göran Rådegran

4. Influence of sGC stimulation on hypoxic pulmonary vasoconstriction

- Jakob Lundgren, David Kylhammar, Petter Hedelin and Göran Rådegran

5. Influence of Levosimendan on hypoxia induced pulmonary vasoconstriction

- Annaeva Wiklund, David Kylhammar and Göran Rådegran

Research students

David Kylhammar, med stud, PhD stud, Lund Univ., Lund, Sweden

Petter Hedelin, MD, Helsingborgs lasarett, Helsingborg, Sweden

Jakob Lundgren, med stud, Lund Univ., Lund, Sweden

Annaeva Wiklund, med stud, Lund Univ., Lund, Sweden

Collaborators

Ylva Hellsten, PhD, Professor, IFI, August Krogh Institute, Copenhagen Univ., Denmark.

Rob Boushel, PhD, The Panum Institute, Copenhagen Univ., Denmark.

Bengt Saltin, Professor, MD, CMRC, Rigshospitalet, Copenhagen, Denmark.'

For more information, please contact:

Göran Rådegran, FOUU-representative

The Clinic for Heart Failure and Valvular Disease, SUS, Lund

Goran.Radegran@med.lu.se