Cardiology

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Pyotr Platonov

CARDIAC ARRHYTHMIAS: FROM GENES TO ELECTROPHYSIOLOGY AND RISK STRATIFICATION

Short biography:

Studied medicine in Pavlov Medical University (St. Petersburg, Russia) 1988-1994. During this time participated in one of the first student exchange programs between the Soviet Union and the USA spending two months at Strong Memorial Hospital, Rochester University School of Medicine. After graduation in 1994 was admitted to the Research Institute of Cardiology (now renamed to the Almazov Federal Heart, Blood and Endocrinology Centre) and from early years of professional carrier combined clinical work with research in electrophysiology.

Started PhD project at Lund University in 1997-1998, while working in Lund under supervision of Professor S Bertil Olsson and continued the research work as a guest researcher until the dissertation defence 2001. Has management experience from part-time employment at Evidence Clinical & Pharmaceutical Research, which was a contract research organisation that managed clinical trials in the former USSR since 1989. Left the company from the position of Vice President Medical Affairs in 2002 after relocation to Sweden.

Received Swedish medical license and cardiology certification 2004 and since then has been working in Arrhythmia Clinic as an electrophysiologist involved in both device surgery and catheter ablations. Since 2005 responsible for cardiogenetic service. In 2006 become an associate professor and in 2014 became an adjunct professor of cardiology at the Department of Cardiology, Lund University

Member of the International Council on Electrocardiology and member of the Board of Trustees of the International Society for Holter and Noninvasive Electrocardiology (ISHNE). Editorial Board member at the Journal of Electrocardiology and Asdociate Editor at the Annals of Noninvasive Electrocardiology.

July 2016 was awarded Fulbright Commission Visiting Scholar grant and moved to the USA in order to pursue research in electrocardiology and cardiogenetics at the University of Rochester, NY until June 2017.

Author of 115 original publications and 32 reviews (2016-12-14). An updated publication list can be retrieved from PubMed.com

Pyotr Platonov’s profile in ResearchGate and Google Scholar

 

Research directions and selected publications:

Since doctoral thesis defence in 2001 (”The role of impaired interatrial conduction in paroxysmal atrial fibrillation: From anatomy to electrophysiology”), atrial fibrillation has been a corner stone of the research program that covers a range of topics:

Atrial anatomy and structural substrate of atrial fibrillation

Genetics of atrial fibrillation

Atrial fibrillation and stroke

 ECG-based diagnostic tools development and validation

P-wave signal-averaged ECG

 Non-invasive assessment of atrial fibrillatory activity

Apart from the atrial fibrillation related topics, the research program has now expanded to cover broader topics of electrocardiology:

Prevention of sudden death; improving risk stratification

This line of research is based on a combination of retrospective and prospective studies on patients who received implantable cardioverter-defibrillators with or without cardiac resynchronisation function for prevention of sudden death due to ischemic or non-ischemic congestive heart failure. The main research objective is identification of imaging- and ECG-based predictors of therapeutic efficacy and increased risk in order to optimize the choice of treatment.

Electrocardiography in acute coronary syndrome

Morphological correlates of dynamic ECG changes caused by myocardial ischemia are studied in two PhD projects that include clinical studies, animal experiments and analysis of large-scale trial data collected in international collaboration.

Inherited cardiac diseases

Risk stratification of patients with inherited cardiac diseases associated with high risk of sudden death is an objective of the ongoing research that includes establishing of a structured follow-up service and register-based studies, such as the Nordic Arrhythmogenic Cardiomyopathy Registry, in which I participate as a Steering Committee member and has a responsibility for coordinating Swedish sites. First publications based on the registry data provided first comprehensive report on the diagnostic accuracy of cardiac ultrasound in relation to cardiac magnetic resonance imaging in the context of ARVC and assessed interobserver variability in detection of epsilon waves, a pathognomonic sign of ARVC that appeared to demonstrate unacceptably high variability in interpretation that may lead to overdiagnosis of the disease:

Pyotr Platonov

pyotr platonov

 

Professor, MD, PhD

Pyotr.Platonov@med.lu.se 
Phone: +46 46 17 10 00
Fax: +46 46 15 78 57

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