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Olga Göransson, Ph.D. Principal Investigator |
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Amélie Gormand, PhD, Post Doc |
| For the past two years, I have been studying the LKB1/AMPK signalling pathway in adipocytes and adipose tissue. I am now investigating the role of this pathway during adipogenesis, the process through which pre-adipocytes differentiate into mature adipocytes. Based on the fact that the LKB1/AMPK signalling pathway controls the cellular energy level, our hypothesis is that it might regulate the expression of adipogenic genes to prevent the cells to undergo a highly energy consuming biological process. |
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Eva Ohlson, Technician |
| Working as a BMA since 2008 when the group formed, I am mainly involved in experiments with primary adipocytes and 3T3-L1 cells. This includes assays to measure biological responses when the cells are stimulated/inhibited with different agents. I also run Western Blot to detect different proteins of interest. |
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Christine Berggreen, PhD Student |
| I joined Olga Göransson’s group as a biomedical undergraduate student and have worked on several projects involving metabolic signaling pathways since then. My primary focus as a PhD student is the unexplored kinase SIK3, which shares structural and regulatory features with AMPK, a key player in metabolic signaling. I am currently investigating the regulation and role of this kinase in adipose tissue, a tissue with high relevance for type 2 diabetes. |
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Emma Henriksson, PhDStudent |
| The major aim of my project is to investigate the regulation and biological role of salt-inducible kinase (SIK) 2, which is a downstream target of LKB1 and belongs to the family of AMPK (AMP-activated protein kinase) - related kinases. Since SIK2 is prominently expressed in adipocytes and also been shown to be up-regulated in diabetic mice it is also highly relevant in a diabetes perspective. |
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Page Manager: Anna Appelberg
Last modified: 2011-05-27