2012-05-15 / Blood Vessels Affected by L-Dopa Treatment of Parkinson's Disease
LU researchers have discovered that small blood vessels in the brain play an important role in the development of L-Dopa induced dyskinesia. The finding could have major implications for the process of developing future treatments in PD.
2012-04-16 / New Stem Cell Found in the Brain
Bagadilico researchers at Lund University have discovered a new stem cell in the adult brain. These cells can proliferate and form several different cell types - most importantly, they can form new brain cells.
2012-04-04 / New Targets for Cell Transplantation in Parkinson's Disease
New research indicates that it is not enough to transplant dopamine-producing cells in Parkinson's disease to alleviate all symptoms. Serotonin cells - controlling sleep, metabolism and mood – will likely have to be included in future transplants.
2012-01-19 / New Research Reveals How α-Synuclein Interacts with Cell Membranes in Parkinson’s Disease
A group of scientists from Bagadilico has found a way to replicate α-synuclein aggregation, implicated in Parkinson's disease progression, on cell membranes to investigate if any of the α-synuclein species can penetrate these membranes.
2011-06-06 / New genetic technique converts skin cells into brain cells
A research breakthrough by Malin Parmar's laboratory has proven that it is possible to reprogram mature cells from human skin directly into brain cells, without passing through the stem cell stage.
2011-04-06 / New discovery proves reason for weight problems in Huntingon’s disease
Huntington’s disease has long been linked to jerky movements. Now, researchers in the TNU laboratory, have shown that the metabolism can also be seriously affected by the hereditary disease. The new laboratory findings provide hope of entirely new treatment methods.
2011-01-19 / Breakthrough suggests damaged proteins travel between cells
The misfolding of abnormal proteins in brain cells is a key element in Parkinson’s disease development. A recent study suggests that the sick proteins slowly move between cells, eventually triggering the destruction of the new host cell. The discovery could potentially lead to new therapeutic strategies aimed at blocking the spread of protein misfolding throughout the brain.
2010-12-13 / New findings suggest novel therapies for dyskinesia
A new study gives hope of an antidyskinetic treatment based on the inhibition of signalling inside cells in the brain’s motor center, the basal ganglia. For the first time intracellular pathways have been shown to play a significant part in L-DOPA induced dyskinesias in Parkinson patients.
2010-10-20 / New developments in Parkinson's drugs
The side effects of the standard medication for Parkinson’s disease have long been a target for brain researchers. Bagadilico's Daniella Rylander has presented new findings in a recently defended PhD thesis that provide hope of more effective medication for those who suffer from the nerve cell disease.
2010-09-06 / Early changes in the hypothalamus identified in Huntington's
Huntington's disease is often linked with involuntary ”dance-like” movements. A new study now shows, for the first time, that changes in the brain's hormonal center, the hypothalamus, occurs more than a decade before the movement disorders appear.
2010-07-19 / New knowledge about the severe side effects of Parkinson's medication
Today's standard medication for Parkinson's is called Levodopa, a drug that can cause severe side effects such as uncontrollable movements. Bagadilico's research team under Deniz Kirik has now found a way to study the mechanisms in the brain that cause these effects. A discovery that has the potential to improve future treatment of Parkinson's.
2010-07-13 / Side effects from Parkinson's cell therapy can be prevented
Parkinson's patients treated with transplanted cells may experience troublesome side effects in the form of involuntary movements. Researchers in Lund and London, among them Bagadilico's Anders Björklund, have now shown that these effects can be prevented.
2010-06-08 / Obstacles to stem cell therapy cleared
Bagadilico researchers have come up with a new technique to prevent tumours developing in connection with stem cell transplantations. The results have been published today in the respected scientific journal PNAS.
Page Manager: Jens Persson
Last modified: 2012-05-09
