Parkinson’s disease and Huntington’s disease are caused by the death of nerve cells in the part of the brain called basal ganglia.
Our goal is to develop and improve treatments for the diseases and to improve quality of life for patients and their families.
In the retail business, the term G-force is routinely used to promote “hi-tech” products, whether it be racing gear, clothing or watches with uniquely durable qualities. In May of this year, a group of Parkinson’s researchers chose that same name for a global alliance with real technological prowess.
Being at the helm of a sprawling research environment can often be an unenviable task. As Ban Ki-Moon and his predecessors at the UN headquarters well know, negotiating diplomatic solutions guided by the lowest common denominator is not exactly a popularity contest. This September, Johan Jakobsson stepped into the role of BAGADILICO’s new Coordinator.
A major breakthrough in the development of stem cell-derived brain cells has put BAGADILICO-researchers on a firm path towards the first ever stem cell transplantations in people with Parkinson’s disease. A new study presents the next generation of transplantable dopamine neurons produced from stem cells. These cells carry the same properties as the dopamine neurons found in the human brain.
Parkinson's disease is strongly linked to the degeneration of the brain’s movement center. In the last decade, the question of where the disease begins has led researchers to a different part of the human anatomy. In 2003, the German neuropathologist Heiko Braak presented a theory suggesting that the disease begins in the gut and spreads to the brain. The idea has since, despite vocal critics, gained a lot of ground. BAGADILICO researchers at Lund University now present the first direct evidence that the disease can actually migrate from the gut to the brain.
The Swedish Research Council and Formas have now completed an interim evaluation of the 20 Linneaus Environments that were awarded grants in 2008, including Bagadilico. The overall results show an impressively high quality. Bagadilico is praised particularly for its ability to boost the careers of promising young researchers, and the ability take basic research discoveries all the way towards clinical application.