Parkinson’s disease and Huntington’s disease are caused by the death of nerve cells in the part of the brain called basal ganglia.
Our goal is to develop and improve treatments for the diseases and to improve quality of life for patients and their families.
The Stem Cell Laboratory for CNS Disease Modeling (CSC Laboratory) in Lund, has created one of the largest iPSC biobanks from patients diagnosed with familial and idiopathic PD, and associated synucleionopathies. iPSCs are obtained by reprogramming patient’s somatic cells into pluripotent stem cells. This unique technique, which allows generating embryonic pluripotent stem cell-like cells, was awarded the Nobel Prize in Medicine in 2012.
The first transplantation of stem cells in patients with Parkinson's disease is almost within reach. However, it remains a challenge for researchers to control stem cells accurately in the lab in order to achieve successful and functional stem cell therapies for patients.
The New York Stem Cell Foundation (NYSCF) announced the 2016 class of NYSCF – Robertson Investigators, welcoming six of the most talented stem cell researchers and neuroscientists from around the world into the NYSCF Investigator Program. This year, Malin Parmar was announced as one of the six award winners. The award will provide funding – $1.5 million over five years.
Tau PET is a new and promising imaging method for Alzheimer’s disease. A case study from Lund University in Sweden now confirms that tau PET images correspond to a higher degree to actual changes in the brain. According to the researchers behind the study, this increases opportunities for developing effective drugs.
Is it possible to convert a patient’s own skin cells into functioning nerve cells? Or insert healthy genes to reprogram the cells of a damaged brain? Stem cell researcher Malin Parmar at Lund University in Sweden is studying these types of issues, in close collaboration with clinical researchers. She is now awarded a prize of SEK 100 000 from the Eric K. Fernström Foundation for her work.